The antimicrobial peptide human beta-defensin 2 promotes itch through Toll-like receptor 4 signaling in mice

被引：19

作者：

Feng, Jing ^{[1
]}

Luo, Jialie ^{[1
]}

Mack, Madison R. ^{[2
]}

Yang, Pu ^{[1
]}

Zhang, Feng ^{[3
]}

Wang, Guan ^{[3
]}

Gong, Xuan ^{[3
]}

Cai, Tao ^{[4
]}

Mei, Zhinan ^{[3
]}

Kim, Brian S. ^{[2
]}

Yin, Shijin ^{[3
]}

Hu, Hongzhen ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Anesthesiol, Ctr Study Itch, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Div Dermatol, St Louis, MO 63110 USA

[3] South Cent Univ Nationalities, Coll Pharm, Wuhan, Hubei, Peoples R China

[4] Chongqing Med Univ, Affiliated Hosp 1, Dept Dermatol, Chongqing, Peoples R China

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2017年 / 140卷 / 03期

基金：

中国国家自然科学基金; 美国国家卫生研究院;

关键词：

ACTIVATION; PAIN;

D O I：

10.1016/j.jaci.2017.03.035

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：885 / +

页数：11

共 14 条

[1] Toll-like receptor 4-dependent activation of dendritic cells by β-defensin 2 [J].

Biragyn, A ;

Ruffini, PA ;

Leifer, CA ;

Klyushnenkova, E ;

Shakhov, A ;

Chertov, O ;

Shirakawa, AK ;

Farber, JM ;

Segal, DM ;

Oppenheim, JJ ;

Kwak, LW .

SCIENCE, 2002, 298 (5595) :1025-1029

[2] Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions [J].

Broggi, Achille ;

Cigni, Clara ;

Zanoni, Ivan ;

Granucci, Francesca .

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2016, (110)

[3] Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPAI [J].

Cruz-Orengo, Lillian ;

Dhaka, Ajay ;

Heuermann, Robert J. ;

Young, Timothy J. ;

Montana, Michael C. ;

Cavanaugh, Eric J. ;

Kim, Donghee ;

Story, Gina M. .

MOLECULAR PAIN, 2008, 4

[4] β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin [J].

Jansen, Patrick A. M. ;

Rodijk-Olthuis, Diana ;

Hollox, Edward J. ;

Kamsteeg, Marijke ;

Tjabringa, Geuranne S. ;

de Jongh, Gys J. ;

van Vlijmen-Willems, Ivonne M. J. J. ;

Bergboer, Judith G. M. ;

van Rossum, Michelle M. ;

de Jong, Elke M. G. J. ;

den Heijer, Martin ;

Evers, Andrea W. M. ;

Bergers, Mieke ;

Armour, John A. L. ;

Zeeuwen, Patrick L. J. M. ;

Schalkwijk, Joost .

PLOS ONE, 2009, 4 (03)

[5] Blind Direction-of-Arrival Estimation with Uniform Circular Array in Presence of Mutual Coupling [J].

Liu, Song ;

Yang, Lisheng ;

Yang, Shizhong ;

Jiang, Qingping ;

Wu, Haowei .

INTERNATIONAL JOURNAL OF ANTENNAS AND PROPAGATION, 2016, 2016

[6] Molecular and cellular mechanisms that initiate pain and itch [J].

Luo, Jialie ;

Feng, Jing ;

Liu, Shenbin ;

Walters, Edgar T. ;

Hu, Hongzhen .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2015, 72 (17) :3201-3223

[7] Mediators of pruritus in psoriasis [J].

Reich, Adam ;

Szepietowski, Jacek C. .

MEDIATORS OF INFLAMMATION, 2007, 2007

[8] Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation [J].

Riol-Blanco, Lorena ;

Ordovas-Montanes, Jose ;

Perro, Mario ;

Naval, Elena ;

Thiriot, Aude ;

Alvarez, David ;

Paust, Silke ;

Wood, John N. ;

von Andrian, Ulrich H. .

NATURE, 2014, 510 (7503) :157-+

[9] Human β-Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2 [J].

Roehrl, Johann ;

Yang, De ;

Oppenheim, Joost J. ;

Hehlgans, Thomas .

JOURNAL OF IMMUNOLOGY, 2010, 184 (12) :6688-6694

[10] Defensins: "Simple" antimicrobial peptides or broad-spectrum molecules? [J].

Suarez-Carmona, Meggy ;

Hubert, Pascale ;

Delvenne, Philippe ;

Herfs, Michael .

CYTOKINE & GROWTH FACTOR REVIEWS, 2015, 26 (03) :361-370

← 1 2 →