DNA strand exchange catalyzed by molecular crowding in PEG solutions

被引:28
作者
Feng, Bobo [1 ]
Frykholm, Karolin [1 ]
Norden, Bengt [1 ]
Westerlund, Fredrik [1 ,2 ]
机构
[1] Chalmers Univ Technol, Dept Chem & Biol Engn, S-41296 Gothenburg, Sweden
[2] Univ Gothenburg, Dept Phys, S-41296 Gothenburg, Sweden
关键词
THERMAL-STABILITY; BASE-STACKING; RECA PROTEIN; STABILIZATION; MECHANISM;
D O I
10.1039/c0cc03117h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA strand exchange is catalyzed by molecular crowding and hydrophobic interactions in concentrated aqueous solutions of polyethylene glycol, a discovery of relevance for understanding the function of recombination enzymes and with potential applications to DNA nanotechnology.
引用
收藏
页码:8231 / 8233
页数:3
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