HALLOYSITE-BASED NANOSYSTEMS FOR BIOMEDICAL APPLICATIONS

被引：17

作者：

Persano, Francesca ^{[1
,2
]}

Gigli, Giuseppe ^{[1
,2
]}

Leporatti, Stefano ^{[2
]}

机构：

[1] Univ Salento, Dept Math & Phys, Via Arnesano, I-73100 Lecce Apulia, Italy

[2] CNR Nanotec Ist Nanotecnol, Via Monteroni, I-73100 Lecce Apulia, Italy

来源：

CLAYS AND CLAY MINERALS | 2021年 / 69卷 / 05期

关键词：

Biomedicine; Drug delivery; Gene Delivery; Halloysite Nanotube Composites; Nanotubes; Tissue Engineering; VIVO TOXICITY EVALUATION; CLAY NANOTUBES; IN-VITRO; CONTROLLED-RELEASE; COMPOSITE SCAFFOLDS; DELIVERY-SYSTEM; NANOCOMPOSITE; TISSUE; CURCUMIN; ACID;

D O I：

10.1007/s42860-021-00135-8

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Halloysite nanotubes (HNTs) are hollow clay nanotubes in the nanometer size range, made up of double-layered aluminum silicate mineral layers. HNTs represent an extremely versatile, safe, and biocompatible nanomaterial, used in a wide range of applications in biomedicine and nanomedicine. For example, they are used as transporters for the controlled release of drugs or genes, in tissue engineering, in the isolation of stem cells and cancer cells, and in bioimaging. Consequently, the assessment of the biocompatibility of HNTs has acquired considerable importance. In recent years, HNT composites have attracted attention due to their improved biocompatibility, compared to HNTs, suggesting potential for applications in tissue engineering or as vehicles for drugs or genes. In this review, recent advances in the application of HNTs and HNT composites in biomedicine are discussed to provide a valuable guide to scientists in the design and development of viable, functional bio-devices for biomedical applications.

引用

页码：501 / 521

页数：21

共 132 条

[1] Halloysite Clay Nanotubes for Controlled Release of Protective Agents [J].