Severe early -onset impulsive compulsive behavior and psychosis in PLA2G6-related juvenile Parkinson's disease

被引:22
作者
Wirth, T. [1 ]
Weibel, S. [2 ]
Montaut, S. [1 ,3 ]
Bigaut, K. [1 ]
Rudolf, G. [1 ]
Chelly, J. [3 ]
Tranchant, C. [1 ,2 ,3 ,4 ]
Anheim, M. [1 ,5 ]
机构
[1] CHU Strasbourg, Hop Hautepierre, Dept Neurol, Strasbourg, France
[2] CHU Strasbourg, Hop Civils, Dept Psychiat, Strasbourg, France
[3] Univ Strasbourg, CNRS UMR7104, INSERM U964, Inst Genet & Biol Mol & Cellulaire IGBMC, Illkirch Graffenstaden, France
[4] Univ Strasbourg, FMTS, Strasbourg, France
[5] Hop Univ Strasbourg, Serv Neurol, 1 Ave Moliere, F-67098 Strasbourg, France
关键词
Parkinson's disease; Impulsive compulsive behavior; Phospholipase-associated neurodegeneration; PLA2G6;
D O I
10.1016/j.parkreldis.2017.05.014
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:127 / 129
页数:3
相关论文
共 5 条
  • [1] PLA2G6-associated Dystonia-Parkinsonism: Case Report and Literature Review
    Karkheiran, Siamak
    Shahidi, Gholam Ali
    Walker, Ruth H.
    Paisan-Ruiz, Coro
    [J]. TREMOR AND OTHER HYPERKINETIC MOVEMENTS, 2015, 5
  • [2] PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron
    Morgan, Neil V.
    Westaway, Shawn K.
    Morton, Jenny E. V.
    Gregory, Allison
    Gissen, Paul
    Sonek, Scott
    Cangul, Hakan
    Coryell, Jason
    Canham, Natalie
    Nardocci, Nardo
    Zorzi, Giovanna
    Pasha, Shanaz
    Rodriguez, Diana
    Desguerre, Isabelle
    Mubaidin, Amar
    Bertini, Enrico
    Trembath, Richard C.
    Simonati, Alessandro
    Schanen, Carolyn
    Johnson, Colin A.
    Levinson, Barbara
    Woods, C. Geoffrey
    Wilmot, Beth
    Kramer, Patricia
    Gitschier, Jane
    Maher, Eamonn R.
    Hayflick, Susan J.
    [J]. NATURE GENETICS, 2006, 38 (07) : 752 - 754
  • [3] Characterization of PLA2G6 as a Locus for Dystonia-Parkinsonism
    Paisan-Ruiz, Coro
    Bhatia, Kailash P.
    Li, Abi
    Hernandez, Dena
    Davis, Mary
    Wood, Nick W.
    Hardy, John
    Houlden, Henry
    Singleton, Andrew
    Schneider, Susanne A.
    [J]. ANNALS OF NEUROLOGY, 2009, 65 (01) : 19 - 23
  • [4] Neurodegenerations with Brain Iron Accumulation
    Schneider, Susanne A.
    [J]. PARKINSONISM & RELATED DISORDERS, 2016, 22 : S21 - S25
  • [5] Homozygous p.D331Y mutation in PLA2G6 in two patients with pure autosomal-recessive early-onset parkinsonism: Further evidence of a fourth phenotype of PLA2G6-associated neurodegeneration
    Xie, Fei
    Cen, Zhidong
    Ouyang, Zhiyuan
    Wu, Sheng
    Xiao, Jianfeng
    Luo, Wei
    [J]. PARKINSONISM & RELATED DISORDERS, 2015, 21 (04) : 420 - 422