Gold-Catalyzed Intramolecular Aminoarylation of Alkenes: C-C Bond Formation through Bimolecular Reductive Elimination

被引：236

作者：

Brenzovich, William E., Jr. ^{[1
]}

Benitez, Diego ^{[2
]}

Lackner, Aaron D. ^{[1
]}

Shunatona, Hunter P. ^{[1
]}

Tkatchouk, Ekaterina ^{[2
]}

Goddard, William A., III ^{[2
]}

Toste, F. Dean ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[2] CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 32期

关键词：

alkenes; C-C bond formation; cyclization; gold; homogeneous catalysis; INTERMOLECULAR ADDITION; ORGANOGOLD COMPLEXES; CARBON NUCLEOPHILES; MILD CONDITIONS; CARBOAMINATION; HYDROAMINATION; REARRANGEMENT; ISOMERIZATION; PYRROLIDINES; SELECTIVITY;

D O I：

10.1002/anie.201002739

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical equation presented) Gold-ilocks and the 3 mol% catalyst: Bimetallic gold bromides allow the room temperature aminoarylation of unactivated terminal olefins with aryl boronic acids using Selectfluor as an oxidant. A catalytic cycle involving gold (I)/gold(III) and a bimolecular reductive elimination for the key C-C bond-forming step is proposed, dppm= bis(diphenylphosphanyl) methane. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5519 / 5522

页数：4

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