Preparation of pediatric patients for treatment with proton beam therapy

被引:16
作者
Mizumoto, Masashi [1 ,2 ]
Oshiro, Yoshiko [1 ]
Ayuzawa, Kaoru [2 ]
Miyamoto, Toshio [2 ]
Okumura, Toshiyuki [1 ]
Fukushima, Takashi [3 ]
Fukushima, Hiroko [3 ]
Ishikawa, Hitoshi [1 ]
Tsuboi, Koji [1 ]
Sakurai, Hideyuki [1 ]
机构
[1] Univ Tsukuba, Dept Radiat Oncol, Tsukuba, Ibaraki 3058575, Japan
[2] Univ Tsukuba, Proton Med Res Ctr, Tsukuba, Ibaraki 3058575, Japan
[3] Univ Tsukuba, Dept Child Hlth, Tsukuba, Ibaraki 3058575, Japan
关键词
Proton beam therapy; Pediatric; Preparation; Radiotherapy; Anesthesia; RADIATION-THERAPY; HEPATOCELLULAR-CARCINOMA; RADIOTHERAPY; ANESTHESIA; PHOTON; CANCER; MEDULLOBLASTOMA; CHILDREN;
D O I
10.1016/j.radonc.2015.01.007
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: Anesthesia is often used in proton beam therapy (PBT) for pediatric patients and this may prolong the treatment time. The aim of the study was to examine preparation of pediatric patients to allow smooth performance of PBT. Material and methods: Preparation was initiated 1-2 days before treatment planning CT and continued for 10 days. The patient first visited the facility to become familiar with the treatment room and staff. As the second step, the patient stayed in the treatment bed for a certain time with their mother, and then stayed on the treatment bed alone. Special fixtures painted with characters, music, and gifts were also prepared. Results: From 2010 to 2014, 111 pediatric patients underwent PBT. These patients were divided into 3 groups: 40 who could follow instructions well (group A, median age: 13.6 years old), 60 who could communicate, but found it difficult to stay alone for a long time (group B, median age: 4.6 years old), and 11 who could not follow instructions (group C, median age: 1.6 years old). Preparation was used for patients in group B. The mean treatment times in groups A, B and C were 13.6, 17.1, and 15.6 min, respectively, on PBT treatment days 2-6, and 11.8, 13.0, and 16.9 min, respectively, for the last 5 days of PBT treatment. The time reduction was significant in group B (p = 0.003). Conclusion: Preparation is useful for pediatric patients who can communicate. This approach allows PBT to be conducted more smoothly over a shorter treatment time. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:245 / 248
页数:4
相关论文
共 19 条
[1]   Safe anesthesia for radiotherapy in pediatric oncology: St. Jude Children's Research Hospital experience, 2004-2006 [J].
Anghelescu, Doralina L. ;
Burgoyne, Laura L. ;
Liu, Wei ;
Hankins, Gtsele M. ;
Cheng, Cheng ;
Beckham, Penny A. ;
Shearer, Jack ;
Norris, Angela L. ;
Kun, Larry E. ;
Bikhazi, George B. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 71 (02) :491-497
[2]   Radiobiological risk estimates of adverse events and secondary cancer for proton and photon radiation therapy of pediatric medulloblastoma [J].
Brodin, N. Patrik ;
Rosenschold, Per Munck A. F. ;
Aznar, Marianne C. ;
Kiil-Berthelsen, Anne ;
Vogelius, Ivan R. ;
Nilsson, Per ;
Lannering, Birgitta ;
Bjork-Eriksson, Thomas .
ACTA ONCOLOGICA, 2011, 50 (06) :806-816
[3]   Repetitive Pediatric Anesthesia in a Non-Hospital Setting [J].
Buchsbaum, Jeffrey C. ;
McMullen, Kevin P. ;
Douglas, James G. ;
Jackson, Jeffrey L. ;
Simoneaux, R. Victor ;
Hines, Matthew ;
Bratton, Jennifer ;
Kerstiens, John ;
Johnstone, Peter A. S. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2013, 85 (05) :1296-1300
[4]   Anesthesia for pediatric external beam radiation therapy [J].
Fortney, JT ;
Halperin, EC ;
Hertz, CM ;
Schulman, SR .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1999, 44 (03) :587-591
[5]   A psychoeducational intervention reduces the need for anesthesia during radiotherapy for young childhood cancer patients [J].
Haeberli, Sonja ;
Grotzer, Michael A. ;
Niggli, Felix K. ;
Landolt, Markus A. ;
Linsenmeier, Claudia ;
Ammann, Roland A. ;
Bodmer, Nicole .
RADIATION ONCOLOGY, 2008, 3 (1)
[6]   Proton beam therapy for hepatocellular carcinoma adjacent to the porta hepatis [J].
Mizumoto, Masashi ;
Tokuuye, Koichi ;
Sugahara, Shinji ;
Nakayama, Hidetsugu ;
Fukumitsu, Nobuyoshi ;
Ohara, Kiyoshi ;
Abei, Masato ;
Shoda, Junichi ;
Tohno, Eriko ;
Minami, Manabu .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 71 (02) :462-467
[7]   PROTON BEAM THERAPY FOR HEPATOCELLULAR CARCINOMA: A COMPARISON OF THREE TREATMENT PROTOCOLS [J].
Mizumoto, Masashi ;
Okumura, Toshiyuki ;
Hashimoto, Takayuki ;
Fukuda, Kuniaki ;
Oshiro, Yoshiko ;
Fukumitsu, Nobuyoshi ;
Abei, Masato ;
Kawaguchi, Atsushi ;
Hayashi, Yasutaka ;
Ookawa, Ayako ;
Hashii, Haruko ;
Kanemoto, Ayae ;
Moritake, Takashi ;
Tohno, Eriko ;
Tsuboi, Koji ;
Sakae, Takeji ;
Sakurai, Hideyuki .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2011, 81 (04) :1039-1045
[8]   PHASE I/II TRIAL OF HYPERFRACTIONATED CONCOMITANT BOOST PROTON RADIOTHERAPY FOR SUPRATENTORIAL GLIOBLASTOMA MULTIFORME [J].
Mizumoto, Masashi ;
Tsuboi, Koji ;
Igaki, Hiroshi ;
Yamamoto, Tetsuya ;
Takano, Shingo ;
Oshiro, Yoshiko ;
Hayashi, Yasutaka ;
Hashii, Haruko ;
Kanemoto, Ayae ;
Nakayama, Hidetsugu ;
Sugahara, Shinji ;
Sakurai, Hideyuki ;
Matsumura, Akira ;
Tokuuye, Koichi .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 77 (01) :98-105
[9]   Clinical results of proton beam therapy for advanced neuroblastoma [J].
Oshiro, Yoshiko ;
Mizumoto, Masashi ;
Okumura, Toshiyuki ;
Sugahara, Shinji ;
Fukushima, Takashi ;
Ishikawa, Hitoshi ;
Nakao, Tomohei ;
Hashimoto, Takayuki ;
Tsuboi, Koji ;
Ohkawa, Haruo ;
Kaneko, Michio ;
Sakurai, Hideyuki .
RADIATION ONCOLOGY, 2013, 8
[10]   Proton beam therapy for unresectable hepatoblastoma in children: Survival in one case [J].
Oshiro, Yoshiko ;
Okumura, Toshiyuki ;
Mizumoto, Masashi ;
Fukushima, Takashi ;
Ishikawa, Hitoshi ;
Hashimoto, Takayuki ;
Tsuboi, Koji ;
Kaneko, Michio ;
Sakurai, Hideyuki .
ACTA ONCOLOGICA, 2013, 52 (03) :600-603