Neuroimaging in the term newborn with neonatal encephalopathy

被引:52
作者
Wisnowski, Jessica L. [1 ,2 ]
Wintermark, Pia [3 ]
Bonifacio, Sonia L. [4 ]
Smyser, Christopher D. [5 ,6 ,7 ]
Barkovich, A. James [8 ]
Edwards, A. David [9 ]
de Vries, Linda S. [10 ]
Inder, Terrie E. [11 ]
Chau, Vann [12 ]
机构
[1] Childrens Hosp Los Angeles, Dept Radiol, 4650 Sunset Blvd,MS 81, Los Angeles, CA 90027 USA
[2] Childrens Hosp Los Angeles, Dept Pediat Neonatol, 4650 Sunset Blvd,MS 81, Los Angeles, CA 90027 USA
[3] McGill Univ, Montreal Childrens Hosp, Hlth Ctr, Res Inst,Dept Pediat Neonatol,Div Newborn Med, 1001 Boul Decarie,Site Glen Block E,EM0-3244, Montreal, PQ H4A 3J1, Canada
[4] Stanford Univ, Lucile Packard Childrens Hosp, Dept Pediat Neonatol, Sch Med,Div Neonatal & Dev Med, 750 Welch Rd,Suite 315, Palo Alto, CA 94304 USA
[5] Washington Univ, Sch Med, Dept Neurol, 660 South Euclid Ave,Campus Box 8111, St Louis, MO 63110 USA
[6] Washington Univ, Sch Med, Dept Radiol, 660 South Euclid Ave,Campus Box 8111, St Louis, MO 63110 USA
[7] Washington Univ, Sch Med, Dept Pediat, 660 South Euclid Ave,Campus Box 8111, St Louis, MO 63110 USA
[8] Univ Calif San Francisco, UCSF Benioff Childrens Hosp, Dept Radiol, 505 Parnassus Ave,M-391, San Francisco, CA 94143 USA
[9] Kings Coll London, Evelina London Childrens Hosp, Ctr Developing Brain, Westminster Bridge Rd, London SE1 7EH, England
[10] Univ Utrecht, Univ Med Ctr Utrecht, Dept Neonatol, Lundlaan 6, NL-3584 EA Utrecht, Netherlands
[11] Harvard Med Sch, Brigham & Womens Hosp, Dept Pediat Newborn Med, Boston, MA 02115 USA
[12] Univ Toronto, Hosp Sick Children, Dept Pediat Neurol, 555 Univ Ave,Room 6513, Toronto, ON M5G 1X8, Canada
[13] Newborn Brain Soc, POB 200783, Roxbury Crossing, MA 02120 USA
基金
加拿大健康研究院; 美国国家卫生研究院;
关键词
Advanced MRI techniques; Asphyxia; Diffusion-tensor imaging; Diffusion-weighted imaging; Hypoxic-ischemic brain injury; Magnetic resonance spectroscopy imaging; Neonatal encephalopathy; Neonates; Outcome prediction; Predictive values; HYPOXIC-ISCHEMIC ENCEPHALOPATHY; MAGNETIC-RESONANCE SPECTROSCOPY; CEREBRAL RESISTANCE INDEX; WHITE-MATTER DEVELOPMENT; BRAIN-INJURY; THERAPEUTIC HYPOTHERMIA; PERINATAL ASPHYXIA; WATER DIFFUSION; IMAGING PATTERN; INFANTS;
D O I
10.1016/j.siny.2021.101304
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neuroimaging is widely used to aid in the diagnosis and clinical management of neonates with neonatal encephalopathy (NE). Yet, despite widespread use clinically, there are few published guidelines on neuroimaging for neonates with NE. This review outlines the primary patterns of brain injury associated with hypoxic-ischemic injury in neonates with NE and their frequency, associated neuropathological features, and risk factors. In addition, it provides an overview of neuroimaging methods, including the most widely used scoring systems used to characterize brain injury in these neonates and their utility as predictive biomarkers. Last, recommendations for neuroimaging in neonates with NE are presented.
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页数:13
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