Fluorescent-magnetic hybrid nanostructures: Preparation, properties, and applications in biology

被引:90
作者
Quarta, Alessandra [1 ,2 ]
Di Corato, Riccardo [1 ,2 ]
Manna, Liberato [1 ,2 ]
Ragusa, Andrea [1 ,2 ]
Pellegrino, Teresa [1 ,2 ]
机构
[1] INFM, CNR, NNL Nanotechnol Lab, Unita Ric IIT, I-73100 Lecce, Italy
[2] Scuola Super ISUFI, I-73100 Lecce, Italy
关键词
fluorescent materials; hybrid materials; magnetic nanoparticles; nanocomposites;
D O I
10.1109/TNB.2007.908989
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Research on nanocomposite materials aims at developing nanoscale composites with innovative optical, chemical, and magnetic properties, all combined in one single nanostructure. In this scenario, nanostructures which show simultaneously fluorescent and magnetic features are of particular interest for pharmaceutical and biomedical applications. In this review, we will focus our attention on magnetic-fluorescent nanocomposite based on colloidal iron oxide nanocrystals combined with different classes of fluorophores which can be either organic dyes, such as fluoresceins, cyanines, porphyrins, or colloidal quantum dots. We will give an overview of the preparation methods of the magnetic-fluorescent nanocomposites that are now available and we will outline the most significant in vitro studies of such nanocomposites on living cells. Some examples of their applications in biology and medicine will also be discussed.
引用
收藏
页码:298 / 308
页数:11
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