Shared features in the pathobiology of babesiosis and malaria

被引：87

作者：

Krause, Peter J. ^{[1
]}

Daily, Johanna ^{[2
]}

Telford, Sam R. ^{[3
]}

Vannier, Edouard ^{[4
]}

Lantos, Paul ^{[2
]}

Spielman, Andrew ^{[2
]}

机构：

[1] Univ Connecticut, Sch Med, Farmington, CT 06030 USA

[2] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

[3] Tufts Univ, Sch Vet Med, North Grafton, MA 01519 USA

[4] Tufts Univ, New England Med Ctr, Boston, MA 02111 USA

来源：

TRENDS IN PARASITOLOGY | 2007年 / 23卷 / 12期

关键词：

D O I：

10.1016/j.pt.2007.09.005

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The pathobiology of malaria has been extensively studied in humans but many questions remain, especially regarding fulminant disease associated with Plasmodium falciparum infection. Babesiosis, recognized since biblical times as an important disease of livestock and more recently as an emerging health problem in humans, is caused by related intraerythrocytic protozoa with a similar pathogenesis and clinical course. Recent studies of cytokine activation and erythrocyte cytoadherence in babesiosis and malaria have exploited these similarities to provide new insights into malaria pathobiology. Continued investigation of similarities and differences in the pathogenesis of babesiosis and malaria should lead to additional fundamental insights for both conditions.

引用

页码：605 / 610

页数：6

共 74 条

[1] Antigenic variation in Babesia bovis occurs through segmental gene conversion of the ves multigene family, within a bidirectional locus of active transcription [J].

Al-Khedery, B ;

Allred, DR .

MOLECULAR MICROBIOLOGY, 2006, 59 (02) :402-414

[2] Antigenic variation and cytoadhesion in Babesia bovis and Plasmodium falciparum:: different logics achieve the same goal [J].

Allred, DR ;

Al-Khedery, B .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2004, 134 (01) :27-35

[3] Babesiosis: persistence in the face of adversity [J].

Allred, DR .

TRENDS IN PARASITOLOGY, 2003, 19 (02) :51-55

[4] High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations [J].

Alves, FP ;

Durlacher, RR ;

Menezes, MJ ;

Krieger, H ;

da Silva, LHP ;

Camargo, EP .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2002, 66 (06) :641-648

[5]

[Anonymous], 1992, EMERGING INFECT MICR

[6]

Armah Henry, 2005, Int J Environ Res Public Health, V2, P123, DOI 10.3390/ijerph2005010123

[7] SPLENIC REQUIREMENT FOR ANTIGENIC VARIATION AND EXPRESSION OF THE VARIANT ANTIGEN ON THE ERYTHROCYTE-MEMBRANE IN CLONED PLASMODIUM-KNOWLESI MALARIA [J].

BARNWELL, JW ;

HOWARD, RJ ;

COON, HG ;

MILLER, LH .

INFECTION AND IMMUNITY, 1983, 40 (03) :985-994

[8]

Beales PF, 2000, T ROY SOC TROP MED H, V94, pS1

[9] Malaria tolerance - for whom the cell tolls? [J].

Boutlis, Craig S. ;

Yeo, Tsin W. ;

Anstey, Nicholas M. .

TRENDS IN PARASITOLOGY, 2006, 22 (08) :371-377

[10] IMMUNITY TO MALARIA - ANTIGENIC VARIATION IN CHRONIC INFECTIONS OF PLASMODIUM KNOWLESI [J].

BROWN, KN ;

BROWN, IN .

NATURE, 1965, 208 (5017) :1286-&

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