FT538: Preclinical Development of an Off-the-Shelf Adoptive NK Cell Immunotherapy with Targeted Disruption of CD38 to Prevent Anti-CD38 Antibody-Mediated Fratricide and Enhance ADCC in Multiple Myeloma When Combined with Daratumumab

被引:14
作者
Bjordahl, Ryan [1 ]
Gaidarova, Svetlana [1 ]
Woan, Karrune [2 ]
Cichocki, Frank [2 ]
Bonello, Greg [1 ]
Robinson, Megan [1 ]
Ruller, Chelsea [1 ]
Pribadi, Mochtar [1 ]
Dinella, Jason [1 ]
Fong, Lauren [1 ]
Huffman, Janel [1 ]
Chu, Hui-yi [1 ]
Lee, Tom [1 ]
Abujarour, Ramzey [1 ]
Kaufman, Dan S. [3 ]
Malmberg, Karl-Johan [4 ]
Miller, Jeffrey S. [2 ]
Valamehr, Bahram [1 ]
机构
[1] Fate Therapeut Inc, San Diego, CA USA
[2] Univ Minnesota, Dept Med, Hematol Oncol & Transplantat, Minneapolis, MN USA
[3] Univ Calif San Diego, Dept Med, Div Regenerat Med, La Jolla, CA 92093 USA
[4] Karolinska Inst, Karolinska Univ Hosp Huddinge, Dept Canc Immunol, Inst Canc Res, Stockholm, Sweden
关键词
D O I
10.1182/blood-2019-131138
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
133
引用
收藏
页数:4
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