Antibacterial Activity of Quaternary Ammonium Salt from Diethylaminoethyl Methacrylate

被引：12

作者：

Mohammed, Makhloufia ^{[1
]}

Tahar, Benaiessa ^{[1
]}

Aiecha, Derdour ^{[2
]}

Eddine, Henni Djamel ^{[3
]}

机构：

[1] Univ Dr Moulay Tahar, Phys Chem Studies Lab, Saida 20000, Algeria

[2] Univ Esenia, Appl Organ Chem Lab, Oran 31000, Algeria

[3] Univ Esenia, Phytopathol Lab, Oran 31000, Algeria

来源：

E-JOURNAL OF CHEMISTRY | 2010年 / 7卷

关键词：

Quaternary ammonium salts; DEAEMA; Antibacterial activity; MIC;

D O I：

10.1155/2010/637549

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A quaternary ammonium salt was synthesized from diethylaminoethyl methacrylate (DEAEMA) by quaternization with hexadecyl bromide. The resultant compound (Am-h) was characterized by FTIR and NMR spectroscopy. Its bactericidal activity was evaluated by determining minimum inhibitory concentration (MIC) values and inhibitory zone diameter against gram positive bacteria (Streptococcus sp.) and gram negative bacteria such as Acenito baumannii, Klebsiella pneumoniae and Proteus sp. respectively. The results showed that the MIC values of the synthesised compound (Am-h) were 2 . mu g/mL against Acenito baumannii, Klebsiella pneumoniae, Proteus sp. and Streptococcus sp.

引用

页码：S61 / S66

页数：6

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