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Structure and gene cluster of the O-antigen of Salmonella enterica 044
被引:6
|作者:
Perepelov, Andrei V.
[1
]
Liu, Bin
[2
,3
]
Senchenkova, Sof'ya N.
[1
]
Shashkov, Alexander S.
[1
]
Guo, Dan
[2
,3
]
Peng, Lu
[2
,3
]
Knirel, Yuriy A.
[1
]
Wang, Lei
[2
,3
]
机构:
[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia
[2] Nankai Univ, TEDA Sch Biol Sci & Biotechnol, Tianjin 300457, Peoples R China
[3] Nankai Univ, TEDA, Tianjin Key Lab Microbial Funct Genom, TEDA Coll, Tianjin 300457, Peoples R China
基金:
俄罗斯基础研究基金会;
关键词:
Salmonella enterica;
Bacterial polysaccharide structure;
O-Antigen;
Lipopolysaccharide;
O-Antigen gene cluster;
D O I:
10.1016/j.carres.2010.07.018
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The O-polysaccharide (O-antigen) of Salmonella enterica O44 was studied by sugar analysis along with 1D and 2D (1)H and (13)C NMR spectroscopy. The following structure of the pentasaccharide repeating unit containing only common monosaccharides was established: beta-D-GlcpNAc 1 down arrow 3 -> 2)-alpha-D-Glcp-(1 -> 6)-alpha-D-Glcp-(1 -> 4)-alpha-D-Galp-(1 -> 3)-beta-D-GlcpNAc-(1 -> The O-antigen gene cluster of S. enterica O44 was sequenced. The gene functions were tentatively assigned by comparison with sequences in the available databases and found to be in full agreement with the S. enterica O44-polysaccharide structure. (C) 2010 Elsevier Ltd. All rights reserved.
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页码:2099 / 2101
页数:3
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