MECHANISM-BASED INHIBITORS OF GLYCOSIDASES: DESIGN AND APPLICATIONS

被引：28

作者：

Kallemeijn, Wouter W. ^{[1
]}

Witte, Martin D. ^{[2
]}

Wennekes, Tom ^{[3
]}

Aerts, Johannes M. F. G. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Med Biochem, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Groningen, Dept Bioorgan Chem, Stratingh Inst Chem, Groningen, Netherlands

[3] Wageningen Univ, Dept Synthet Organ Chem, NL-6700 AP Wageningen, Netherlands

来源：

ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, VOL 71 | 2014年 / 71卷

关键词：

ACID-BETA-GLUCOSIDASE; GLYCOSYL-ENZYME INTERMEDIATE; ACTIVE-SITE NUCLEOPHILE; ACTIVITY-BASED PROBES; GLUCOCEREBROSIDE-CLEAVING ENZYME; LACTASE-PHLORHIZIN HYDROLASE; SUBSTRATE-ASSISTED CATALYSIS; SUCRASE-ISOMALTASE COMPLEX; PROTEIN-PROFILING PROBES; X-RAY CRYSTALLOGRAPHY;

D O I：

10.1016/B978-0-12-800128-8.00004-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：297 / 338

页数：42

共 273 条

[21]

ATSUMI S, 1993, CANCER RES, V53, P4896

[22] A Plant-Derived Recombinant Human Glucocerebrosidase Enzyme-A Preclinical and Phase I Investigation [J].

Aviezer, David ;

Brill-Almon, Einat ;

Shaaltiel, Yoseph ;

Hashmueli, Sharon ;

Bartfeld, Daniel ;

Mizrachi, Sarah ;

Liberman, Yael ;

Freeman, Arnold ;

Zimran, Ari ;

Galun, Eithan .

PLOS ONE, 2009, 4 (03)

[23] Lysosomal disorders: From storage to cellular damage [J].

Ballabio, Andrea ;

Gieselmann, Volkmar .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2009, 1793 (04) :684-696

[24] REACTIONS OF ANIONIC NUCLEOPHILES WITH ALPHA-D-GLUCOPYRANOSYL FLUORIDE IN AQUEOUS-SOLUTION THROUGH A CONCERTED, A(N)D(N) (S(N)2) MECHANISM [J].

BANAIT, NS ;

JENCKS, WP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (21) :7951-7958

[25] REPLACEMENT THERAPY FOR INHERITED ENZYME DEFICIENCY - MACROPHAGE-TARGETED GLUCOCEREBROSIDASE FOR GAUCHERS-DISEASE [J].

BARTON, NW ;

BRADY, RO ;

DAMBROSIA, JM ;

DIBISCEGLIE, AM ;

DOPPELT, SH ;

HILL, SC ;

MANKIN, HJ ;

MURRAY, GJ ;

PARKER, RI ;

ARGOFF, CE ;

GREWAL, RP ;

YU, KT .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (21) :1464-1470

[26] Interdiction of Sphingolipid Metabolism to Improve Standard Cancer Therapies [J].

Beckham, Thomas H. ;

Cheng, Joseph C. ;

Marrison, S. Tucker ;

Norris, James S. ;

Liu, Xiang .

ROLE OF SPHINGOLIPIDS IN CANCER DEVELOPMENT AND THERAPY, 2013, 117 :1-36

[27] Pharmacological chaperone therapy for Gaucher disease: a patent review [J].

Benito, Juan M. ;

Garcia Fernandez, Jose M. ;

Ortiz Mellet, Carmen .

EXPERT OPINION ON THERAPEUTIC PATENTS, 2011, 21 (06) :885-903

[28] The uptake of recombinant glucocerebrosidases by blood monocytes from type 1 Gaucher disease patients is variable [J].

Berger, Juliette ;

Stirnemann, Jerome ;

Bourgne, Celine ;

Pereira, Bruno ;

Pigeon, Pascale ;

Heraoui, Djazia ;

Froissart, Roseline ;

Rapatel, Chantal ;

Rose, Christian ;

Belmatoug, Nadia ;

Berger, Marc G. .

BRITISH JOURNAL OF HAEMATOLOGY, 2012, 157 (02) :274-277

[29] pH-Dependent Si-Fluorescein Hypochlorous Acid Fluorescent Probe: Spirocycle Ring-Opening and Excess Hypochlorous Acid-Induced Chlorination [J].

Best, Quinn A. ;

Sattenapally, Narsimha ;

Dyer, Daniel J. ;

Scott, Colleen N. ;

McCarroll, Matthew E. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (36) :13365-13370

[30] A chimeric mouse model of Gaucher disease [J].

Beutler, E ;

West, C ;

Torbett, BE ;

Deguchi, H .

MOLECULAR MEDICINE, 2002, 8 (05) :247-250

← 1 2 3 4 5 6 7 8 9 10 →