A solvent-free synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one in a ball mill

被引：2
作者：
Zhang, Xiong [1 ]
Wang, Biao [2 ]
Zhang, Binbin [2 ]
Wang, Yifeng [2 ]
机构：
[1] Zhejiang Int Studies Univ, Sch Sci & Technol, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Univ Technol, State Key Lab Breeding Base Green Chem Synth Tech, Key Lab Green Pesticides & Cleaner Prod Technol Z, Hangzhou, Zhejiang, Peoples R China
来源：
GREEN CHEMISTRY LETTERS AND REVIEWS | 2018年 / 11卷 / 04期
关键词：
Solvent-free; ball mill; 1-(4-chlorophenyl)pyrazolidin-3-one; 4-chlorophenyl hydrazine; methyl acrylate; ALDOL REACTION; (S)-PROLINE-CONTAINING DIPEPTIDES; IONIC LIQUIDS; SOLID-STATE; ESTERS; COMPLEXES; ALKYNES; COPPER;
D O I：
10.1080/17518253.2018.1526332
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An easy, solvent-free method for the synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one has been achieved by grinding 4-chlorophenyl hydrazine and methyl acrylate in the presence of base in a ball mill. A systematic investigation of the reaction has been made in order to study the various factors affecting the reaction. [GRAPHICS] .
引用
收藏
页码：414 / 418
页数：5
相关论文
共 32 条
  • [1] Solvent-free synthesis of unsaturated amino esters in a ball-mill
    Baron, Alice
    Martinez, Jean
    Lamaty, Frederic
    [J]. TETRAHEDRON LETTERS, 2010, 51 (48) : 6246 - 6249
  • [2] Cheng X, 2005, CHINESE CHEM LETT, V16, P1327
  • [3] Suzuki cross-couplings of (hetero)aryl chlorides in the solid-state
    Cravotto, Giancarlo
    Garella, Davide
    Tagliapietra, Silvia
    Stolle, Achim
    Schuessler, Stefan
    Leonhardt, Silke E. S.
    Ondruschka, Bernd
    [J]. NEW JOURNAL OF CHEMISTRY, 2012, 36 (06) : 1304 - 1307
  • [4] Systematic Study of a Solvent-Free Mechanochemically Induced Domino Oxa-Michael-Aldol Reaction in a Ball Mill
    Gerard, Emilie M. C.
    Sahin, Huelya
    Encinas, Arantxa
    Braese, Stefan
    [J]. SYNLETT, 2008, (17) : 2702 - 2704
  • [5] Efficient ball-mill procedure in the 'green' asymmetric aldol reaction organocatalyzed by (S)-proline-containing dipeptides in the presence of water
    Hernandez, Jose G.
    Juaristi, Eusebio
    [J]. TETRAHEDRON, 2011, 67 (36) : 6953 - 6959
  • [6] Asymmetric Aldol Reaction Organocatalyzed by (S)-Proline-Containing Dipeptides: Improved Stereoinduction under Solvent-Free Conditions
    Hernandez, Jose G.
    Juaristi, Eusebio
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2011, 76 (05) : 1464 - 1467
  • [7] Solvent-free synthesis of the smallest rotaxane prepared to date
    Hsu, Chi-Chieh
    Chen, Na-Chia
    Lai, Chien-Chen
    Liu, Yi-Hung
    Peng, Shie-Ming
    Chiu, Sheng-Hsien
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (39) : 7475 - 7478
  • [8] Kaupp G., 2003, ADV TECHNOLOGIES BAS, V83
  • [9] Mechanochemistry
    Kipp, S
    Sepelák, V
    Becker, KD
    [J]. CHEMIE IN UNSERER ZEIT, 2005, 39 (06) : 384 - 392
  • [10] Fast and Selective Dehydrogenative C-H/C-H Arylation Using Niechanochemistry
    Lou, Shao-Jie
    Mao, Yang-Jie
    Xu, Dan-Qian
    He, Jiang-Qi
    Chen, Qi
    Xu, Zhen-Yuan
    [J]. ACS CATALYSIS, 2016, 6 (06): : 3890 - 3894
1234