Leucomidines A-C, novel alkaloids from Leuconotis griffithii

被引：37

作者：

Motegi, Midori ^{[1
]}

Nugroho, Alfarius Eko ^{[1
]}

Hirasawa, Yusuke ^{[1
]}

Arai, Takashi ^{[1
]}

Hadi, A. Hamid A. ^{[2
]}

Morita, Hiroshi ^{[1
]}

机构：

[1] Hoshi Univ, Fac Pharmaceut Sci, Shinagawa Ku, Tokyo 1428501, Japan

[2] Univ Malaya, Dept Chem, Fac Sci, Kuala Lumpur 50603, Malaysia

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 10期

关键词：

Indole alkaloid; Quinazoline alkaloid; Leuconotis griffithii; Apocynaceae; MOLECULAR-FORCE FIELD; DENSITY; MMFF94;

D O I：

10.1016/j.tetlet.2011.12.116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel indole alkaloids and new quinazoline alkaloids, namely leucomidines A-C (1-3), were isolated from the barks of Leuconotis griffithii. The structures including the absolute configuration were elucidated on the basis of spectroscopic data, chemical means, and CD calculations. The quinazoline alkaloid, 3, is proposed to be derived from the same biogenetic precursor as the indole alkaloids 1 and 2. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1227 / 1230

页数：4

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