Presence of viral RNA of SARS-CoV-2 in conjunctival swab specimens of COVID-19 patients

被引：63

作者：

Kumar, Kiran ^{[1
]}

Prakash, Akshata A. ^{[1
]}

Gangasagara, Suresh Babu ^{[1
]}

Rathod, Sujatha B. L. ^{[1
]}

Ravi, K. ^{[2
]}

Rangaiah, Ambica ^{[3
]}

Shankar, Sathyanarayan Muthur ^{[3
]}

Basawarajappa, Shantala Gowdara ^{[3
]}

Bhushan, Shashi ^{[4
]}

Neeraja, T. G. ^{[1
]}

Khandenahalli, Srinivas ^{[1
]}

Swetha, M. ^{[1
]}

Gupta, Priyam ^{[1
]}

Sampritha, U. C. ^{[1
]}

Prasad, Guru N. S. ^{[1
]}

Jayanthi, Chakravarthy Raghunathan ^{[5
]}

机构：

[1] Minto Ophthalm Hosp, Bangalore Med Coll & Res Inst, Dept Ophthalmol, Bangalore, Karnataka, India

[2] Bangalore Med Coll & Res Inst, Dept Med, Bangalore, Karnataka, India

[3] Bangalore Med Coll & Res Inst, Dept Microbiol, Bangalore, Karnataka, India

[4] Bangalore Med Coll & Res Inst, Dept Pulm Med, Bangalore, Karnataka, India

[5] Bangalore Med Coll & Res Inst, Dept Pharmacol, Bangalore, Karnataka, India

来源：

INDIAN JOURNAL OF OPHTHALMOLOGY | 2020年 / 68卷 / 06期

关键词：

Conjunctival swab; coronavirus disease-19; nasopharyngeal swab; SARS-CoV-2; RESPIRATORY SYNDROME CORONAVIRUS;

D O I：

10.4103/ijo.IJO_1287_20

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To detect the presence of viral RNA of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in conjunctival swab specimens of coronavirus disease-19 (COVID-19) patients. Methods: Forty-five COVID-19 patients positive for real-time reverse transcription-polymerase chain reaction (RT-PCR) for SARS-CoV-2 in nasopharyngeal swab with or without ocular manifestations were included in the study. The conjunctival swab of each patient was collected by an ophthalmologist posted for COVID duty. Results: Out of 45 patients, 35 (77.77%) were males and the rest were females. The mean age was 31.26 +/- 12.81 years. None of the patients had any ocular manifestations. One (2.23%) out of 45 patients was positive for RT-PCR SARS-CoV-2 in the conjunctival swab. Conclusion: This study shows that SARS-CoV-2 can be detected in conjunctival swabs of confirmed cases of COVID-19 patients. Though the positivity rate of detecting SARS-CoV-2 in conjunctival swabs is very less, care should be exercised during the ocular examination of patients of COVID-19.

引用

页码：1015 / 1017

页数：3

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