Bioactive Peptides Derived from Seaweed Protein and Their Health Benefits: Antihypertensive, Antioxidant, and Antidiabetic Properties

被引:198
作者
Admassu, Habtamu [1 ,2 ]
Gasmalla, Mohammed Abdalbasit. A. [1 ,4 ]
Yang, Ruijin [1 ,3 ]
Zhao, Wei [1 ,3 ]
机构
[1] Jiangnan Univ, State Key Lab Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[2] Addis Ababa Sci & Technol Univ, Dept Food Proc Engn, POB 16417, Addis Ababa 1000, Ethiopia
[3] Jiangnan Univ, Sch Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[4] Omdurman Islamic Univ, Fac Sci & Technol, Dept Nutr & Food Technol, POB 382, Khartoum 14415, Sudan
基金
中国国家自然科学基金;
关键词
antioxidant activity; antihypertensive effect; antidiabetic properties; bioactive peptides; seaweed; ENZYME-INHIBITORY PEPTIDES; IN-VITRO; BIOLOGICAL-ACTIVITIES; UNDARIA-PINNATIFIDA; ENHANCED EXTRACTION; FUCUS-VESICULOSUS; PALMARIA-PALMATA; RED ALGA; IDENTIFICATION; HYDROLYSATE;
D O I
10.1111/1750-3841.14011
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Cardiovascular diseases and diabetes are the biggest causes of death globally. Therefore, prevention of these diseases is a focus of pharmaceuticals and functional food manufacturers. This review summarizes recent research trends and scientific knowledge in seaweed protein-derived peptides with particular emphasis on production, isolation and potential health impacts in prevention of hypertension, diabetes and oxidative stress. The current status and future prospects of bioactive peptides are also discussed. Bioactive peptides have strong potential for use in therapeutic drug and functional food formulation in health management strategy, especially cardiovascular disease and diabetes. Seaweeds can be used as sustainable protein sources in the production of these peptide-based drugs and functional foods for preventing such diseases. Many studies have reported that peptides showing angiotensin converting enzyme inhibition, antihypertensive, antioxidative and antidiabetics activities, have been successfully isolated from seaweed. However, further research is needed in large-scale production of these peptides, efficient isolation methods, interactions with functional foods and other pharmaceuticals, and their ease to digestion in in vivo studies and safety to validate the health benefits of these peptides.
引用
收藏
页码:6 / 16
页数:11
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