Methyl 2-(2-{[(benzyloxy)carbonyl]amino}propan-2-yl)-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylate

被引：2

作者：

Shang, Zhenhua ^{[1
]}

Ha, Jing ^{[1
]}

Yu, Yifeng ^{[1
]}

Zhao, Xiaodan ^{[1
]}

机构：

[1] Hebei Univ Sci & Technol, Coll Chem & Pharmaceut Engn, Shijiazhuang 050018, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷

关键词：

D O I：

10.1107/S1600536811016278

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C17H19N3O6, the dihedral angle between the two aromatic rings is 45.9 (1)degrees. The crystal structure is stabilized through intermolecular N-H...O hydrogen bonds and intramolecular O-H...O hydrogen bonds are also present.

引用

页码：O1336 / U2115

页数：11

共 6 条

[1]

*BRUK AXS INC, 1997, SADABS SMART SAINT

[2] SYNTHESIS OF 5,6-DIHYDROXY-2-PHENYL-4-PYRIMIDINECARBOXYLIC ACID, METHYL-ESTER, A CORRECTED STRUCTURE [J].

CULBERTSON, TP .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1979, 16 (07) :1423-1424

[3] 6-Amino-2,5-bis(pivaloylamino)pyrimidin-4(3H)-one dihydrate [J].

Fun, Hoong-Kun ;

Balasubramani, Kasthuri ;

Hazra, Anita ;

Das, Manas Kumar ;

Goswami, Shyamaprosad .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 :01484-U1722

[4] Methyl 6-methyl-2-oxo-4-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate [J].

Shang, Zhen-Hua ;

Shang, Qing .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 :O2280-O2281

[5] A short history of SHELX [J].

Sheldrick, George M. .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122

[6] Raltegravir with optimized background therapy for resistant HIV-1 infection [J].

Steigbigel, Roy T. ;

Cooper, David A. ;

Kumar, Princy N. ;

Eron, Joseph E. ;

Schechter, Mauro ;

Markowitz, Martin ;

Loutfy, Mona R. ;

Lennox, Jeffrey L. ;

Gatell, Jose M. ;

Rockstroh, Jurgen K. ;

Katlama, Christine ;

Yeni, Patrick ;

Lazzarin, Adriano ;

Clotet, Bonaventura ;

Zhao, Jing ;

Chen, Joshua ;

Ryan, Desmond M. ;

Rhodes, Rand R. ;

Killar, John A. ;

Gilde, Lucinda R. ;

Strohmaier, Kim M. ;

Meibohm, Anne R. ;

Miller, Michael D. ;

Hazuda, Daria J. ;

Nessly, Michael L. ;

DiNubile, Mark J. ;

Isaacs, Robin D. ;

Nguyen, Bach-Yen ;

Teppler, Hedy .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (04) :339-354

← 1 →