Antiretroviral therapy in Indian setting: When & what to start with, when & what to switch to?

被引：23

作者：

Kumarasamy, N. ^{[1
,3
]}

Patel, Atul ^{[2
,3
]}

Pujari, Sanjay ^{[3
,4
]}

机构：

[1] YRG CARE Med Ctr, Voluntary Hlth Serv, Madras 600113, Tamil Nadu, India

[2] Vedant Inst Med Sci, Ahmadabad, Gujarat, India

[3] Inst Infect Dis, Pune, Maharashtra, India

[4] HIVMAI, Pune, Maharashtra, India

来源：

INDIAN JOURNAL OF MEDICAL RESEARCH | 2011年 / 134卷 / 06期

基金：

英国惠康基金;

关键词：

Antiretroviral drugs; antiretroviral therapy; ART; CD4; HIV; IRIS; viral load; RECONSTITUTION INFLAMMATORY SYNDROME; HIV-INFECTED PATIENTS; CD4 CELL COUNTS; COST-EFFECTIVENESS ANALYSIS; ZIDOVUDINE-INDUCED ANEMIA; LONG-TERM EFFICACY; LINE VIRAL LOAD; IMMUNE RECONSTITUTION; RISK-FACTORS; DRUG-RESISTANCE;

D O I：

10.4103/0971-5916.92626

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

With the rapid scale up of antiretroviral therapy, there is a dramatic decline in HIV related morbidity and mortality in both developed and developing countries. Several new safe antiretroviral, and newer class of drugs and monitoring assays are developed recently. As a result the treatment guideline for the management of HIV disease continue to change. This review focuses on evolving science on Indian policy - antiretroviral therapy initiation, which drugs to start with, when to change the initial regimen and what to change.

引用

页码：787 / 800

页数：14

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