Tafamidis

被引：74

作者：

Said, Gerard ^{[1
]}

Grippon, Seden ^{[2
]}

Kirkpatrick, Peter

机构：

[1] Univ Pitie Salpetriere, Ctr Hosp, Dept Neurol, F-75651 Paris 13, France

[2] IMS Hlth, London NW1 6JB, England

来源：

NATURE REVIEWS DRUG DISCOVERY | 2012年 / 11卷 / 03期

关键词：

FAMILIAL AMYLOID POLYNEUROPATHY;

D O I：

10.1038/nrd3675

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In November 2011, tafamidis (Vyndaqel; Pfizer), a small molecule that inhibits the dissociation of transthyretin tetramers, was granted marketing authorization by the European Commission for the treatment of transthyretin amyloidosis in adult patients with stage 1 symptomatic polyneuropathy to delay peripheral neurological impairment. © 2012 Macmillan Publishers Limited. All rights reserved.

引用

页码：185 / 186

页数：2

共 7 条

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