Relapsed Acute Myeloid Leukemia Is Less Sensitive to Venetoclax plus Azacitidine Due to Leukemia Stem Cell Resistance Driven By Fatty Acid Metabolism and Can be Overcome By Pharmacologic Inhibition of CPT1

被引：4

作者：

Pollyea, Daniel A. ^{[1
]}

Jones, Courtney L. ^{[1
]}

Stevens, Brett M. ^{[2
]}

Pei, Shanshan ^{[1
]}

D'Alessandro, Angelo ^{[1
]}

Culp-Hill, Rachel ^{[1
]}

Abbott, Diana ^{[3
]}

Hammes, Andrew ^{[4
]}

Dugan, James ^{[5
]}

Gutman, Jonathan A. ^{[1
]}

Purev, Enkhtsetseg ^{[1
]}

Smith, Clayton ^{[4
]}

Jordan, Craig T. ^{[2
]}

机构：

[1] Univ Colorado, Denver, CO 80202 USA

[2] Univ Colorado, Div Hematol, Dept Med, Anschutz Med Campus, Aurora, CO USA

[3] Univ Colorado Denver, Dept Biostat & Bioinformat, Aurora, CO USA

[4] Univ Colorado, Div Hematol, Aurora, CO USA

[5] Univ Colorado, Dept Hematol, Denver, CO 80202 USA

来源：

关键词：

D O I：

10.1182/blood-2018-99-111507

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

432

引用

页数：3

共 2 条