Clustering of nosocomial Candida kefyr infections among hematological patients in a university hospital:: Molecular typing of the strains by PFGE and RAPD

被引：6

作者：

Kalkanci, A. ^{[1
]}

Saracli, M. A. ^{[2
]}

Guzel, O. ^{[3
]}

Yildiran, S. T. ^{[2
]}

Senol, E. ^{[3
]}

Kustimur, S. ^{[1
]}

机构：

[1] Gazi Univ, Fac Med, Dept Microbiol, TR-06500 Ankara, Turkey

[2] Gulhane Mil Med Acad, Dept Microbiol, Ankara, Turkey

[3] Gazi Univ, Fac Med, Dept Infect Dis, TR-06500 Ankara, Turkey

来源：

JOURNAL DE MYCOLOGIE MEDICALE | 2007年 / 17卷 / 04期

关键词：

Candida kefyr; hematology; nososcomial; infection; AP-PCR; PFGE; RAPD;

D O I：

10.1016/j.mycmed.2007.09.003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study spreading over a span of eight months described Candida kefyr infections in hematolology patients from a Turkish University hospital. A total of 18 strains were isolated from various body locations of 18 patients. DNA fingerprinting of the isolates was performed by using randomly amplified polymorphic DNA (RAPD) method and karyotyping by pulsed-field get electrophoresis (PFGE). RAPD analysis of all the C. kefyr strains revealed that strains collected from 18 different patients exhibited seven different genotypes, while those were six in PFGE. Taken together, this is probably the first molecular survey of C. kefyr infections in the hematology unit documenting nosocomial transmission of C. kefyr isolates. (C) 2007 Elsevier Masson SAS. All rights reserved.

引用

页码：250 / 255

页数：6

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