Microwave accelerated azomethine ylide cycloaddition with Baylis-Hillman adducts

被引：5

作者：

Keesari, Nagarjuna Reddy ^{[1
,2
]}

Mudavath, Somanath ^{[1
]}

Rao, M. V. Krishna ^{[1
,2
]}

Sridhar, Balasubramanian ^{[3
]}

Subba Reddy, B. V. ^{[1
,2
]}

机构：

[1] CSIR Indian Inst Chem Technol, Fluoro & Agrochem, Hyderabad, India

[2] Acad Sci & Innovat Res AcSIR, New Delhi, India

[3] CSIR Indian Inst Chem Technol, Lab X Ray Crystallog, Hyderabad, India

来源：

SYNTHETIC COMMUNICATIONS | 2020年 / 50卷 / 07期

关键词：

Amino acids; azomethine ylides; cycloaddition; fused heterocycles; isatins; ONE-POT; 1,3-DIPOLAR CYCLOADDITION; HETEROCYCLES; SPIROPYRROLIDINE; CONSTRUCTION; PYRROLIDINE; SCAFFOLDS; LIGANDS; ISATIN;

D O I：

10.1080/00397911.2020.1725975

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azomethine ylides generated in situ from isatins and alpha-amino acids undergo smooth 1,3-dipolar cycloaddition with olefins derived from the Baylis-Hillman reaction to produce fused 2-quinolinone derivatives in good yields with high selectivity. The use of microwave irradiation makes this method quite simple and rapid to generate polycyclic frameworks in a single step.

引用

页码：973 / 979

页数：7

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