Synthesis of polyazamacrocyclic compounds via modified Richman-Atkins cyclization of β-trimethylsilylethanesulfonamides

被引：34

作者：

Hoye, RC ^{[1
]}

Richman, JE

Dantas, GA

Lightbourne, MF

Shinneman, LS

机构：

[1] Macalester Coll, Dept Chem, St Paul, MN 55105 USA

[2] Univ Minnesota, Biol Proc Technol Inst, St Paul, MN 55108 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 08期

关键词：

D O I：

10.1021/jo001639o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Richman-Atkins cyclization remains one of the most widely used methods for the preparation of macrocyclic polyamines. The use of beta -trimethylsilylethanesulfonamides (SES-sulfonamides) for the preparation of polyazamacrocyclic compounds is described. This expands existing Richman-Atkins sulfonamide macrocyclization methodology, and it successfully enables preparation of labile polyaza [n](1,4)naphthalenophane and polyaza[n](9,10)anthracenophanes, not previously available in appreciable quantities.

引用

页码：2722 / 2725

页数：4

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