Is there an association between systemic lupus erythematosus and periodontal disease?

被引:12
作者
Calderaro, Debora Cerqueira [1 ]
Ferreira, Gilda Aparecida [2 ]
Souza de Mendonca, Santuza Maria [3 ]
Correa, Joice Dias [4 ]
Santos, Fabricia Xavier [5 ]
Capinam Sancao, Joao Guilherme [5 ]
da Silva, Tarcilia Aparecida [6 ]
Teixeira, Antonio Lucio [7 ]
机构
[1] Univ Fed Minas Gerais, Sch Med, Postgrad Program Infect & Parasit Dis, Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Sch Med, Dept Locomotor Syst, Belo Horizonte, MG, Brazil
[3] Ctr Univ Newton Paiva, Sch Dent, Belo Horizonte, MG, Brazil
[4] Univ Fed Minas Gerais, Inst Biol Sci, Postgrad Program Cell Biol, Belo Horizonte, MG, Brazil
[5] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil
[6] Univ Fed Minas Gerais, Sch Dent, Dept Clin Pathol & Surg, Belo Horizonte, MG, Brazil
[7] Univ Fed Minas Gerais, Sch Med, Belo Horizonte, MG, Brazil
关键词
Systemic lupus erythematosus; Periodontitis; Chronic periodontitis; HEALTH;
D O I
10.1016/j.rbre.2015.08.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Periodontal disease results from the interaction between pathogenic bacteria that colonize supragingival and subgingival biofilms and the host, triggering an inflammatory response, with systemic effects leading to immune-mediated destruction of the attachment apparatus and loss of supporting alveolar bone. Immunological pathways and predisposing genetic factors common to periodontal disease and rheumatic diseases, including systemic lupus erythematosus, have been described. Case reports have suggested greater severity of periodontal disease in patients with systemic lupus erythematosus. However, studies evaluating the influence of the treatment of one disease on the clinical and laboratory manifestations of the other have yielded conflicting results. (C) 2015 Elsevier Editora Ltda. All rights reserved.
引用
收藏
页码:280 / 284
页数:5
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