Crystallization-induced dynamic resolution (CIDR) and its application to the synthesis of unnatural N-substituted amino acids derived from aroylacrylic acids

被引：39

作者：

Kolarovic, A

Berkes, D

Baran, P

Povazanec, F

机构：

[1] Slovak Univ Technol Bratislava, Dept Organ Chem, SK-81237 Bratislava, Slovakia

[2] Univ Puerto Rico, Dept Chem, San Juan, PR 00931 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 13期

关键词：

amino acid derivatives; asymmetric induction; dynamic resolution; addition; amino alcohols;

D O I：

10.1016/S0040-4039(01)00221-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective conjugate addition of chiral amino alcohols affords a simple and inexpensive access to a wide variety of N-functionalized homophenylalanine derivatives. Limitations and conditions for application of CIDR to this system were studied. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2579 / 2582

页数：4

共 7 条

[1] Stereoselective sodium borohydride reduction, catalyzed by manganese(II) chloride, of γ-oxo-α-amino acids.: A practical approach to syn-γ-hydroxy-α-amino acids [J].