GATA Switches as Developmental Drivers

被引：224
作者：
Bresnick, Emery H. [1 ,2 ]
Lee, Hsiang-Ying [1 ,2 ]
Fujiwara, Tohru [1 ,2 ]
Johnson, Kirby D. [1 ,2 ]
Keles, Sunduz [3 ]
机构：
[1] Univ Wisconsin, Sch Med & Publ Hlth, Paul Carbone Comprehens Canc Ctr, Div Hematol Oncol,Dept Pharmacol, Madison, WI 53705 USA
[2] Univ Wisconsin, Sch Med & Publ Hlth, Paul Carbone Comprehens Canc Ctr, Dept Med, Madison, WI 53705 USA
[3] Univ Wisconsin, Sch Med & Publ Hlth, Dept Biostat & Med Informat, Madison, WI 53706 USA
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2010年 / 285卷 / 41期
基金：
美国国家卫生研究院;
关键词：
TRANSCRIPTION FACTOR GATA-1; CHROMATIN DOMAIN ACTIVATION; ZINC-FINGER PROTEIN; DNA-BINDING; GENE-EXPRESSION; ERYTHROID DEVELOPMENT; DEPENDENT REGULATION; HEMATOPOIETIC-CELLS; FACTOR INTERPLAY; GLOBIN LOCUS;
D O I：
10.1074/jbc.R110.159079
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Transcriptional networks orchestrate complex developmental processes. Such networks are commonly instigated by master regulators of development. Considerable progress has been made in elucidating GATA factor-dependent genetic networks that control blood cell development. GATA-2 is required for the genesis and/or function of hematopoietic stem cells, whereas GATA-1 drives the differentiation of hematopoietic progenitors into a subset of the blood cell lineages. GATA-1 directly represses Gata2 transcription, and this involves GATA-1-mediated displacement of GATA-2 from chromatin, a process termed a GATA switch. GATA switches occur at numerous loci with critical functions, indicating that they are widely utilized developmental control tools.
引用
收藏
页码：31087 / 31093
页数：7
相关论文
共 100 条
[1]   CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation [J].
Blobel, GA ;
Nakajima, T ;
Eckner, R ;
Montminy, M ;
Orkin, SH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (05) :2061-2066
[2]   Developmental control via GATA factor interplay at chromatin domains [J].
Bresnick, EH ;
Martowicz, ML ;
Pal, S ;
Johnson, KD .
JOURNAL OF CELLULAR PHYSIOLOGY, 2005, 205 (01) :1-9
[3]   Establishment and regulation of chromatin domains: Mechanistic insights from studies of hemoglobin synthesis [J].
Bresnick, Emery H. ;
Johnson, Kirby D. ;
Kim, Shin-Il ;
Im, Hogune .
PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 81, 2006, 81 :435-471
[4]   A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in β-globin expression and erythroid development [J].
Bultman, SJ ;
Gebuhr, TC ;
Magnuson, T .
GENES & DEVELOPMENT, 2005, 19 (23) :2849-2861
[5]   Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation [J].
Cantor, AB ;
Katz, SG ;
Orkin, SH .
MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (12) :4268-4279
[6]   Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage [J].
Cantor, Alan B. ;
Iwasaki, Hirorni ;
Arinobu, Yojiro ;
Moran, Tyler B. ;
Shigematsu, Hirokazu ;
Sullivan, Matthew R. ;
Akashi, Koichi ;
Orkin, Stuart H. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2008, 205 (03) :611-624
[7]   Hemangioblast commitment in the avian allantois:: Cellular and molecular aspects [J].
Caprioli, A ;
Minko, K ;
Drevon, C ;
Eichmann, A ;
Dieterlen-Lièvre, F ;
Jaffredo, T .
DEVELOPMENTAL BIOLOGY, 2001, 238 (01) :64-78
[8]   GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis [J].
Chang, AN ;
Cantor, AB ;
Fujiwara, Y ;
Lodish, MB ;
Droho, S ;
Crispino, JD ;
Orkin, SH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (14) :9237-9242
[9]  
Charron F, 1999, MOL CELL BIOL, V19, P4355
[10]   GATA transcription factors and cardiac development [J].
Charron, F ;
Nemer, M .
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 1999, 10 (01) :85-91
12345678910