The Emerging Role of Gas Plasma in Oncotherapy

被引：94
作者：
Dai, Xiaofeng [1 ,2 ]
Bazaka, Kateryna [3 ,4 ]
Richard, Derek J. [4 ,5 ,6 ,7 ]
Thompson, Erik W. [4 ,5 ,6 ,7 ]
Ostrikov, Kostya [3 ,4 ]
机构：
[1] Jiangnan Univ, Wuxi Sch Med, Wuxi, Peoples R China
[2] Jiangnan Univ, Sch Biotechnol, Wuxi, Peoples R China
[3] Queensland Univ Technol, Sch Chem Phys & Mech Engn, Brisbane, Qld 4059, Australia
[4] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia
[5] Translat Res Inst, Woolloongabba, Qld 4102, Australia
[6] Univ Melbourne, St Vincents Hosp, Dept Surg, Melbourne, Vic 3065, Australia
[7] Queensland Univ Technol, Sch Biomed Sci, Brisbane, Qld 4059, Australia
来源：
TRENDS IN BIOTECHNOLOGY | 2018年 / 36卷 / 11期
基金：
澳大利亚研究理事会; 中国国家自然科学基金;
关键词：
COLD ATMOSPHERIC PLASMA; BARRIER DISCHARGE PLASMA; NONTHERMAL PLASMA; PRESSURE PLASMA; BREAST-CANCER; ARGON PLASMA; CHRONIC WOUNDS; CELLS; ADHESION; HEAD;
D O I：
10.1016/j.tibtech.2018.06.010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that can supplement the existing set of treatment modalities and, when combined with other therapies, enhance their selectivity and efficacy against resistant cancers. With further optimisation in production and administration of plasma treatment, plasma-enabled therapy has a strong potential to mature as a tool for selectively curing highly resistant solid tumours. Although intense preclinical studies have been conducted to exploit the unique traits of plasma as an oncotherapy, few clinical studies are underway. This review identifies types of cancers and patient groups that most likely benefit from plasma oncotherapy, to introduce clinical practitioners to plasma therapy and accelerate the speed of translating plasma for cancer control in clinics.
引用
收藏
页码：1183 / 1198
页数：16
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