Biopolymer network geometries: Characterization, regeneration, and elastic properties

被引：103

作者：

Lindstroem, Stefan B. ^{[1
]}

Vader, David A. ^{[2
]}

Kulachenko, Artem ^{[3
]}

Weitz, David A. ^{[2
]}

机构：

[1] Royal Inst Technol, Dept Fiber & Polymer Technol, SE-10044 Stockholm, Sweden

[2] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

[3] Royal Inst Technol, Dept Solid Mech, SE-10044 Stockholm, Sweden

来源：

PHYSICAL REVIEW E | 2010年 / 82卷 / 05期

基金：

美国国家科学基金会;

关键词：

NONLINEAR ELASTICITY; COLLAGEN; STRESS;

D O I：

10.1103/PhysRevE.82.051905

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We study the geometry of biopolymer networks and effects of the geometry on bulk mechanical properties. It is shown numerically that the physical network geometry can be quantified statistically and regenerated from its statistical description, so that the regenerated network exhibits the same network mechanics as the physical network in the elastic regime. A collagen-I biopolymer network is used for validation. The method enables parametric studies of the network geometry, whose parameters are often difficult to vary independently in experiments.

引用

页数：5

共 22 条

[11] Nonlinear elasticity of stiff biopolymers connected by flexible linkers [J].

Kasza, K. E. ;

Koenderink, G. H. ;

Lin, Y. C. ;

Broedersz, C. P. ;

Messner, W. ;

Nakamura, F. ;

Stossel, T. P. ;

MacKintosh, F. C. ;

Weitz, D. A. .

PHYSICAL REVIEW E, 2009, 79 (04)

[12] Three-dimensional reconstruction of statistically optimal unit cells of polydisperse particulate composites from microtomography [J].

Lee, H. ;

Brandyberry, M. ;

Tudor, A. ;

Matous, K. .

PHYSICAL REVIEW E, 2009, 80 (06)

[13] ELASTICITY OF SEMIFLEXIBLE BIOPOLYMER NETWORKS [J].

MACKINTOSH, FC ;

KAS, J ;

JANMEY, PA .

PHYSICAL REVIEW LETTERS, 1995, 75 (24) :4425-4428

[14] Alternative explanation of stiffening in cross-linked semiflexible networks [J].

Onck, PR ;

Koeman, T ;

van Dillen, T ;

van der Giessen, E .

PHYSICAL REVIEW LETTERS, 2005, 95 (17)

[15] Stress-strain experiments on individual collagen fibrils [J].

Shen, Zhilei L. ;

Dodge, Mohammad Reza ;

Kahn, Harold ;

Ballarini, Roberto ;

Eppell, Steven J. .

BIOPHYSICAL JOURNAL, 2008, 95 (08) :3956-3963

[16] An algorithm for extracting the network geometry of three-dimensional collagen gels [J].

Stein, Andrew M. ;

Vader, David A. ;

Jawerth, Louise M. ;

Weitz, David A. ;

Sander, Leonard M. .

JOURNAL OF MICROSCOPY, 2008, 232 (03) :463-475

[17] Nonlinear elasticity in biological gels [J].

Storm, C ;

Pastore, JJ ;

MacKintosh, FC ;

Lubensky, TC ;

Janmey, PA .

NATURE, 2005, 435 (7039) :191-194

[18]

Vader D. A., 2010, THESIS HARVARD U

[19] Micromechanical testing of individual collagen fibrils [J].

van der Rijt, Joost A. J. ;

van der Werf, Kees O. ;

Bennink, Martin L. ;

Dijkstra, Pieter J. ;

Feijen, Jan .

MACROMOLECULAR BIOSCIENCE, 2006, 6 (09) :697-702

[20] Elasticity of Floppy and Stiff Random Networks [J].

Wyart, M. ;

Liang, H. ;

Kabla, A. ;

Mahadevan, L. .

PHYSICAL REVIEW LETTERS, 2008, 101 (21)

← 1 2 3 →