Determination and correlation of the solubility for diosgenin in alcohol solvents

被引：38

作者：

Chen, Fei-xiong ^{[1
]}

Zhao, Ming-rui ^{[2
]}

Liu, Chuo-chuo ^{[1
]}

Peng, Fei-fei ^{[3
]}

Ren, Bao-zeng ^{[1
]}

机构：

[1] Zhengzhou Univ, Coll Chem Engn & Energy, Zhengzhou 450001, Peoples R China

[2] Henan Med Coll Staff & Workers, Zhengzhou 451191, Henan, Peoples R China

[3] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

JOURNAL OF CHEMICAL THERMODYNAMICS | 2012年 / 50卷

关键词：

(Solid plus liquid) equilibrium; Solubility; Diosgenin; SOLIDS; WATER;

D O I：

10.1016/j.jct.2012.02.002

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

Using a laser monitoring technique, the solubility of diosgenin in ethanol, 1-propanol, 1-butanol, isobutyl alcohol, tert-butanol, 1-pentanol, and iso-octyl alcohol was measured over the temperature range from (290.15 to 330.15) K at atmospheric pressure. Its corresponding (solid + liquid) equilibrium data will provide essential support for industrial design and further theoretical studies. From the experimental results, the solubility of diosgenin in ethanol, 1-propanol, 1-butanol, isobutyl alcohol, tert-butanol, 1-pentanol, and iso-octyl alcohol was found to increase with increasing temperature and decrease with the increase of the polarity of the alcohols solvents. The Apelblat equation, the ideal model and the lambda h equation were used to correlate the solubility values. The results showed that the three models mentioned above agreed well with the experimental data. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1 / 6

页数：6

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