Hyperbaric exposure with high oxygen concentration enhances oxidative capacity of neurornuscular units

被引：25

作者：

Ishihara, A ^{[1
]}

Kawano, F

Okiura, T

Morimatsu, F

Ohira, Y

机构：

[1] Kyoto Univ, Grad Sch Human & Environm Studies, Neurochem Lab, Kyoto 6068501, Japan

[2] Osaka Univ, Grad Sch Med, Toyonaka, Osaka 5600043, Japan

[3] Nippon Meat Packers Inc, Ctr Res & Dev, Tsukuba, Ibaraki 3002646, Japan

来源：

NEUROSCIENCE RESEARCH | 2005年 / 52卷 / 02期

关键词：

plantaris muscle; retrograde neuronal labeling; skeletal muscle fiber; soleus muscle; spinal motoneuron; succinate dehydrogenase activity;

D O I：

10.1016/j.neures.2005.03.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of hyperbaric exposure with high oxygen concentration on spinal motoneurons and the skeletal muscle fibers that they innervate were investigated. Five-week-old male rats were exposed to a hyperbaric (1.25 atmospheric pressure) environment with a high oxygen concentration (35.0%) for 6 h daily. The number, cell body size, and oxidative enzyme activity of motoneurons innervating the soleus and plantaris muscles were examined after 8 weeks of hyperbaric exposure. In addition, the fiber type distribution, cell size, and oxidative enzyme activity of the slow soleus and fast plantaris muscles were examined. The oxidative enzyme activity of alpha motoneurons innervating the soleus and plantaris muscles increased after hyperbaric exposure, irrespective of their cell body sizes. The percentage of high-oxidative fibers in the soleus and plantaris muscles increased after hyperbaric exposure. The oxidative enzyme activity of all types of fibers in the soleus and plantaris muscles increased after hyperbaric exposure. It is concluded that hyperbaric exposure with high oxygen concentration enhances the oxidative capacity of neuromuscular units. (c) 2005 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

引用

页码：146 / 152

页数：7

共 30 条

[1] AN HRP STUDY OF THE RELATION BETWEEN CELL-SIZE AND MOTOR UNIT TYPE IN CAT ANKLE EXTENSOR MOTO-NEURONS [J].

BURKE, RE ;

DUM, RP ;

FLESHMAN, JW ;

GLENN, LL ;

LEVTOV, A ;

ODONOVAN, MJ ;

PINTER, MJ .

JOURNAL OF COMPARATIVE NEUROLOGY, 1982, 209 (01) :17-28

[2] MARKED AND VARIABLE INHIBITION BY CHEMICAL FIXATION OF CYTOCHROME-OXIDASE AND SUCCINATE-DEHYDROGENASE IN SINGLE MOTONEURONS [J].

CHALMERS, GR ;

EDGERTON, VR .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1989, 37 (06) :899-901

[3] SINGLE MOTONEURON SUCCINATE-DEHYDROGENASE ACTIVITY [J].

CHALMERS, GR ;

EDGERTON, VR .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1989, 37 (07) :1107-1114

[4] ADAPTABILITY OF THE OXIDATIVE CAPACITY OF MOTONEURONS [J].

CHALMERS, GR ;

ROY, RR ;

EDGERTON, VR .

BRAIN RESEARCH, 1992, 570 (1-2) :1-10

[5] MOTONEURON AND MUSCLE-FIBER SUCCINATE-DEHYDROGENASE ACTIVITY IN CONTROL AND OVERLOADED PLANTARIS [J].

CHALMERS, GR ;

ROY, RR ;

EDGERTON, VR .

JOURNAL OF APPLIED PHYSIOLOGY, 1991, 71 (04) :1589-1592

[6] SOMA SIZE AND OXIDATIVE ENZYME-ACTIVITY IN NORMAL AND CHRONICALLY STIMULATED MOTONEURONS OF THE CATS SPINAL-CORD [J].

DONSELAAR, Y ;

KERNELL, D ;

EERBEEK, O .

BRAIN RESEARCH, 1986, 385 (01) :22-29

[7] Cell size and succinate dehydrogenase activity of different types of fibers in different regions of the tibialis anterior muscle in mice and rats [J].

Hirofuji, C ;

Nakatani, T ;

Ishihara, A ;

Tanaka, M ;

Itoh, K ;

Itoh, M ;

Katsuta, S ;

Ibata, Y .

ACTA HISTOCHEMICA ET CYTOCHEMICA, 2000, 33 (04) :295-303

[8]

Ishihara A, 1997, AVIAT SPACE ENVIR MD, V68, P421

[9] Effects of running exercise during recovery from hindlimb unloading on soleus muscle fibers and their spinal motoneurons in rats [J].

Ishihara, A ;

Kawano, F ;

Ishioka, N ;

Oishi, H ;

Higashibata, A ;

Shimazu, T ;

Ohira, Y .

NEUROSCIENCE RESEARCH, 2004, 48 (02) :119-127

[10] SUCCINATE-DEHYDROGENASE ACTIVITY AND SOMA SIZE OF MOTONEURONS INNERVATING DIFFERENT PORTIONS OF THE RAT TIBIALIS ANTERIOR [J].

ISHIHARA, A ;

ROY, RR ;

EDGERTON, VR .

NEUROSCIENCE, 1995, 68 (03) :813-822

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