Outcome of retinoblastoma in east Africa

被引：86

作者：

Bowman, R. J. C.

Mafwiri, M.

Luthert, P.

Luande, J.

Wood, A.

机构：

[1] CCBRT Hosp, Dar Es Salaam 23310, Tanzania

[2] London Sch Hyg & Trop Med, Int Ctr Eye Hlth, London WC1, England

[3] Muhimbili Univ, Coll Hlth Sci, Dar Es Salaam, Tanzania

[4] Inst Ophthalmol, London, England

[5] Ocean Rd Canc Inst, Dar Es Salaam, Tanzania

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 50卷 / 01期

关键词：

Africa; outcome; presentation; retinoblastoma;

D O I：

10.1002/pbc.21080

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We estimated the proportion of patients reaching a pediatric ophthalmology unit (Comprehensive Community Based Rehabilitation for Tanzania Disability Hospital, CCBRT) or an oncology unit (ORCI) in east Africa and investigated presentation, histology, and treatment outcomes of patients with retinoblastoma. A 5-year retrospective study identified 91 patients, representing approximately 18% of the nationwide total. Mean lag time was 10 months (standard deviation (SD)=17) and mean follow-up was 8 months (SD=11, range 0-40, n=91). Thirty months disease-free survival probability was 0.23 (standard error=0.07). Outcomes for retinoblastoma in Africa remain poor. The data presented here suggest strategies for improving the outcomes, including encouraging earlier presentation and establishment of multi-disciplinary treatment centers.

引用

页码：160 / 162

页数：3

共 19 条

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BenEzra D, 1976, J Pediatr Ophthalmol, V13, P340

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