Novel Ionic Liquid with Both Lewis and Bronsted Acid Sites for Michael Addition

被引：11

作者：

Jiang, Xiaoyue ^{[2
]}

Ye, Weidong ^{[2
]}

Song, Xiaohua ^{[2
]}

Ma, Wenxin ^{[2
]}

Lao, Xuejun ^{[2
]}

Shen, Runpu ^{[1
]}

机构：

[1] Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China

[2] Zhejiang Med Co Ltd, Xinchang Pharmaceut Factory, Hangzhou 312500, Zhejiang, Peoples R China

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2011年 / 12卷 / 11期

基金：

中国国家自然科学基金;

关键词：

novel ionic liquid; Michael addition; Lewis and Bronsted acid sites; CARBONYL-COMPOUNDS; CATALYST;

D O I：

10.3390/ijms12117438

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ionic liquid with both Lewis and Bronsted acid sites has been synthesized and its catalytic activities for Michael addition were carefully studied. The novel ionic liquid was stable to water and could be used in aqueous solution. The molar ratio of the Lewis and Bronsted acid sites could be adjusted to match different reactions. The results showed that the novel ionic liquid was very efficient for Michael addition with good to excellent yields within several min. Operational simplicity, high stability to water and air, small amount used, low cost of the catalyst used, high yields, chemoselectivity, applicability to large-scale reactions and reusability are the key features of this methodology, which indicated that this novel ionic liquid also holds great potential for environmentally friendly processes.

引用

页码：7438 / 7444

页数：7

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