Effects of dietary quercetin on growth, antioxidant capacity, immune response and immune-related gene expression in snakehead fish, Channa argus

被引：35

作者：

Kong, Yuxin ^{[1
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Tian, Jiaxin ^{[1
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Niu, Xiaotian ^{[1
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Li, Min ^{[1
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Kong, Yidi ^{[1
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Li, Ruoming ^{[1
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Chen, Xiumei ^{[1
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Wang, Guiqin ^{[1
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机构：

[1] Jilin Agr Univ, Coll Anim Sci & Technol, Changchun 130118, Jilin, Peoples R China

[2] Jilin Agr Univ, Lab Anim Prod & Qual Secur, Minist Educ, Changchun 130118, Jilin, Peoples R China

[3] Jilin Agr Univ, Joint Lab Modern Agr Technol Int Cooperat, Minist Educ, Changchun 130118, Jilin, Peoples R China

[4] Jilin Agr Univ, Jilin Prov Key Lab Anim Nutr & Feed Sci, Changchun 130118, Jilin, Peoples R China

来源：

AQUACULTURE REPORTS | 2022年 / 26卷

关键词：

Quercetin; Channa argus; Growthperformance and feed utilization; Antioxidant; Immuneresponse; Immunegene; ALLIUM-MONGOLICUM-REGEL; AEROMONAS-HYDROPHILA INFECTION; DISEASE RESISTANCE; OXIDATIVE STRESS; COMMON CARP; VITAMIN-C; FLAVONOIDS; HORMONES; ENHANCE; IMMUNOSTIMULANTS;

D O I：

10.1016/j.aqrep.2022.101314

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

The present study aimed to evaluate the effects of quercetin-supplemented in diet on growth, antioxidant capacity and immune response and immune-related gene expression of Channa argus (C. argus) (initial weight, 24.50 +/- 0.24 g). A basal diet was supplemented with quercetin at 0, 150, 300 or 450 mg kg-1 and feed to C. argus 56 days. Weight gain (WG) and specific growth rate (SGR) were significantly increased (P < .05), and feed conversion ratio (FCR) were significantly decreased (P < .05) with the increase of dietary quercetin levels from 0 to 450 mg kg(-1). Supplemented quercetin (150, 300 or 450 mg kg(-1)) significantly enhanced (P < .05) serum or tissues superoxide dismutase (SOD), catalase (CAT), total antioxidant capacity (T-AOC), glutathione S-transferase (GST), glutathione peroxidase (GSH-Px), lysozyme (LZM) activity and complement 3 (C3), complement 4 (C4), immunoglobulin M (IgM) concentration. Meanwhile, quercetin administration significantly up-regulated (P < .05) the expression of immune-related cytokines (interleukin-1 beta[IL-1 beta], tumor necrosis factor-alpha[TNF-alpha], interleukin-8[IL-8], interleukin-10[IL-10]) in liver, spleen, kidney and intestine of C. argus. These results indi-cated that dietary supplement quercetin could enhance growth, antioxidant capacity, immune response and regulated immune-related genes expression of C. argus, with greatest effects in C. argus given 300 mg kg(-1) quercetin for 56 days.

引用

页数：12

共 47 条

[1] Quercetin and naringenin abate diethylnitrosamine/acetylaminofluorene-induced hepatocarcinogenesis in Wistar rats: the roles of oxidative stress, inflammation and cell apoptosis [J].