Dittrichia graveolens (L.) Greuter, a Rapidly Spreading Invasive Plant: Chemistry and Bioactivity

被引:10
作者
Ponticelli, Maria [1 ]
Lela, Ludovica [1 ]
Russo, Daniela [1 ,2 ]
Faraone, Immacolata [1 ,2 ]
Sinisgalli, Chiara [1 ,2 ]
Mustapha, Mayssa Ben [3 ]
Esposito, Germana [4 ]
Jannet, Hichem Ben [3 ]
Costantino, Valeria [4 ]
Milella, Luigi [1 ]
机构
[1] Univ Basilicata, Dept Sci, Viale Ateneo Lucano 10, I-85100 Potenza, Italy
[2] Spinoff BioActiPlant Srl, Viale Ateneo Lucano 10, I-85100 Potenza, Italy
[3] Univ Monastir, Lab Heterocycl Chem Nat Prod & React, Med Chem & Nat Prod LR11ES39, Fac Sci Monastir, Monastir 5000, Tunisia
[4] Univ Naples Federico II, Dept Pharm, I-80131 Naples, Italy
关键词
Dittrichia graveolens (L; ) Greuter; Inula graveolens L; stinkwort; Asteraceae; phenolic compounds; borneol; terpenes; flavonoids; invasive species; INULA-GRAVEOLENS; ESSENTIAL OIL; CHEMICAL-COMPOSITION; VOLATILE CONSTITUENTS; MEDICINAL-PLANTS; SESQUITERPENES; EXTRACTION; PHENOLOGY; ENTERITIS; LACTONES;
D O I
10.3390/molecules27030895
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dittrichia graveolens L. Greuter belonging to the Asteraceae family, is an aromatic herbaceous plant native to the Mediterranean region. This plant species has been extensively studied for its biological activities, including antioxidant, antitumor, antimicrobial, antifungal, anti-inflammatory, anticholinesterase, and antityrosinase, and for its peculiar metabolic profile. In particular, bioactivities are related to terpenes and flavonoids metabolites, such as borneol (40), tomentosin (189), inuviscolide (204). However, D. graveolens is also well known for causing health problems both in animals and humans. Moreover, the species is currently undergoing a dramatic northward expansion of its native range related to climate change, now including North Europe, California, and Australia. This review represents an updated overview of the 52 literature papers published in Scopus and PubMed dealing with expansion, chemistry (262 different compounds), pharmacological effects, and toxicology of D. graveolens up to October 2021. The review is intended to boost further studies to determine the molecular pathways involved in the observed activities, bioavailability, and clinical studies to explore new potential applications.
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页数:20
相关论文
共 70 条
[31]   Review on plant antimicrobials: a mechanistic viewpoint [J].
Khameneh, Bahman ;
Iranshahy, Milad ;
Soheili, Vahid ;
Bazzaz, Bibi Sedigheh Fazly .
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL, 2019, 8 (1)
[32]  
Khan H, 2022, PHYTOCHEM REV, V21, P385, DOI [10.1007/s11101-021-09771-3, 10.1371/journal.pone.0262543]
[33]   Therapeutic Potential of Volatile Terpenes and Terpenoids from Forests for Inflammatory Diseases [J].
Kim, Taejoon ;
Song, Bokyeong ;
Cho, Kyoung Sang ;
Lee, Im-Soon .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (06)
[34]   New Insights into the Exploitation ofVitis viniferaL. cv. Aglianico Leaf Extracts for Nutraceutical Purposes [J].
Labanca, Fabiana ;
Faraone, Immacolata ;
Nole, Maria Rosaria ;
Hornedo-Ortega, Ruth ;
Russo, Daniela ;
Garcia-Parrilla, Maria Carmen ;
Chiummiento, Lucia ;
Bonomo, Maria Grazia ;
Milella, Luigi .
ANTIOXIDANTS, 2020, 9 (08) :1-16
[35]   ICHTHYOTOXIC SESQUITERPENES AND XANTHANOLIDES FROM DITTRICHIA-GRAVEOLENS [J].
LANZETTA, R ;
LAMA, G ;
MAURIELLO, G ;
PARRILLI, M ;
RACIOPPI, R ;
SODANO, G .
PHYTOCHEMISTRY, 1991, 30 (04) :1121-1124
[36]   Rapid evolution of phenology during range expansion with recent climate change [J].
Lustenhouwer, Nicky ;
Wilschut, Rutger A. ;
Williams, Jennifer L. ;
van der Putten, Wim H. ;
Levine, Jonathan M. .
GLOBAL CHANGE BIOLOGY, 2018, 24 (02) :E534-E544
[37]   Extraction, separation and isolation of essential oils from natural matrices by supercritical CO2 [J].
Marongiu, B ;
Piras, A ;
Pani, F ;
Porcedda, S ;
Ballero, M .
FLAVOUR AND FRAGRANCE JOURNAL, 2003, 18 (06) :505-509
[38]   Medical ethnobotany of the Tabarkins, a Northern Italian (Ligurian) minority in south-western Sardinia [J].
Maxia, Andrea ;
Lancioni, Maria Cristina ;
Balia, Alessandra Nicoletta ;
Alborghetti, Raffaella ;
Pieroni, Andrea ;
Loi, Maria Cecilia .
GENETIC RESOURCES AND CROP EVOLUTION, 2008, 55 (06) :911-924
[39]  
Miladinovic DL, 2016, NAT PROD COMMUN, V11, P865
[40]   Composition of the essential oil of Dittrichia graveolens (L.) Greuter [J].
Mirza, M ;
Ahmadi, L .
JOURNAL OF ESSENTIAL OIL RESEARCH, 2000, 12 (04) :507-508