Live birth following a single oocyte fertilized with ICSI and embryo biopsy at blastocyst stage: a case report

被引：0

作者：

Sciorio, Romualdo ^{[1
,2
]}

Antonini, Elena ^{[2
]}

Engl, Bruno ^{[2
]}

机构：

[1] Royal Infirm Edinburgh NHS Trust, EFREC, Edinburgh Assisted Concept Programme, Edinburgh EH16 4SA, Midlothian, Scotland

[2] Donna Salus Womens Hlth & Fertil, Bolzano, Italy

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2020年 / 36卷 / 11期

关键词：

In vitro fertilization (IVF); intracytoplasmic sperm injection (ICSI); fertilization and embryo culture; blastocyst biopsy; preimplantation genetic testing; live birth; ANEUPLOIDY; CULTURE; PREGNANCIES; OXYGEN;

D O I：

10.1080/09513590.2020.1751110

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this report, we present a case of a couple who obtained a live birth with a single oocyte fertilized by ICSI. Two oocytes were collected at 35.5 hours (h) post trigger and both were at metaphase II when sperm injection was performed (38 h). At 18 h post injection, one oocyte was fertilized, developed to the blastocyst stage and underwent to trophectoderm biopsy for preimplantation genetic testing on day 5. Following biopsy, the blastocyst was vitrified and 4 h after warming procedure, the euploid blastocyst was replaced to the uterine cavity. Healthy live birth was obtained after 39 weeks of gestation.

引用

页码：1038 / 1041

页数：4

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