The influence of calcium ions and ionophore A23187 on microrheological characteristics of erythrocytes by new model ektacytometry

被引:0
|
作者
Chunyi, W
Yanjun, Z [1 ]
Weibo, K
机构
[1] Beijing Polytech Univ, Ctr Biomed Engn, Biomech & Med Informat Inst, Beijing 100022, Peoples R China
[2] Peking Univ, Sch Med, Dept Biophys, Beijing 100083, Peoples R China
关键词
new model ektacytometry; calcium ions; ionophore A23187; erythrocyte deformation;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
After rabbit's erythrocytes were treated with different concentrations of intercellular Ca2+ and ionophore A23187 respectively, the orientation index (DI)(d) and small deformation index (Dl)d of rabbit erythrocytes were measured by new model ektacytometry. The results demonstrated that (DI)(or) and (DT)(d) decreased while the concentration of intercellular Ca2+ or ionophore A23187 increased. Suggesting that the deformability of erythrocytes was reduced after treatment with intercellular Ca2+; or ionophore A23187. Furthermore, the effect of ionophore A23187 on the microrheology of erythrocytes is more notable than that of intercellular Ca2+.
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页码:19 / 23
页数:5
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