Update on endocrine hypertension

被引:5
作者
Lechner, B. [1 ]
Heinrich, D. [1 ]
Noelting, S. [1 ]
Osswald-Kopp, A. [1 ]
Rubinstein, G. [1 ]
Sauerbeck, J. [2 ]
Beuschlein, F. [1 ]
Reincke, M. [1 ]
机构
[1] Klinikum Univ Munchen, Med Klin & Poliklin 4, Campus Innenstadt,Ziemssenstr 1, D-80336 Munich, Germany
[2] Klinikum Univ Munchen, Klin & Poliklin Nukl Med, Munich, Germany
来源
INTERNIST | 2018年 / 59卷 / 11期
关键词
Primary aldosteronism; Pheochromocytoma; Paraganglioma; Cushing syndrome; Hypertension; secondary; CLINICAL-PRACTICE GUIDELINE; PRIMARY ALDOSTERONISM; CUSHINGS-SYNDROME; ADRENAL INCIDENTALOMAS; EUROPEAN-SOCIETY; BLOOD-PRESSURE; MANAGEMENT; DIAGNOSIS; PHEOCHROMOCYTOMA; PREVALENCE;
D O I
10.1007/s00108-018-0505-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Endocrine disorders are the most common causes of secondary hypertension. Early diagnosis and specific treatment are crucial for improvement of the prognosis. This article provides an overview on which clinical constellations point to an increased risk of secondary causes of hypertension. These include spontaneous hypokalemia, young age at onset of hypertension, adrenal incidentaloma and therapy refractive arterial hypertension. The basic diagnostics include determination of the aldosterone to renin ratio, measurement of free plasma metanephrines and a1mg dexamethasone suppression test. Borderline results require repeated control testing and/or confirmatory testing under standardized test conditions. In cases of repeatedly conspicuous results referral to aspecialized clinic should be considered for further clarification and confirmation of the diagnosis. Imaging diagnostics may constitute an adjunct to laboratory testing after the diagnosis has been confirmed. Therapeutic algorithms vary depending on the underlying endocrine disease.
引用
收藏
页码:1163 / 1179
页数:17
相关论文
共 18 条
[1]   Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors [J].
Fassnacht, Martin ;
Arlt, Wiebke ;
Bancos, Irina ;
Dralle, Henning ;
Newell-Price, John ;
Sahdev, Anju ;
Tabarin, Antoine ;
Terzolo, Massimo ;
Tsagarakis, Stylianos ;
Dekkers, Olaf M. .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2016, 175 (02) :G1-G34
[2]   The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline [J].
Funder, John W. ;
Carey, Robert M. ;
Mantero, Franco ;
Murad, M. Hassan ;
Reincke, Martin ;
Shibata, Hirotaka ;
Stowasser, Michael ;
Young, William F., Jr. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2016, 101 (05) :1889-1916
[3]   Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study [J].
Hundemer, Gregory L. ;
Curhan, Gary C. ;
Yozamp, Nicholas ;
Wang, Molin ;
Vaidya, Anand .
LANCET DIABETES & ENDOCRINOLOGY, 2018, 6 (01) :51-59
[4]  
Kearney PM, 2005, LANCET, V365, P217, DOI 10.1016/S0140-6736(05)70151-3
[5]   Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline [J].
Lenders, Jacques W. M. ;
Duh, Quan-Yang ;
Eisenhofer, Graeme ;
Gimenez-Roqueplo, Anne-Paule ;
Grebe, Stefan K. G. ;
Murad, Mohammad Hassan ;
Naruse, Mitsuhide ;
Pacak, Karel ;
Young, William F., Jr. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (06) :1915-1942
[6]   Phaeochromocytoma [J].
Lenders, JWM ;
Eisenhofer, G ;
Mannelli, M ;
Pacak, K .
LANCET, 2005, 366 (9486) :665-675
[7]   Diagnosis and Differential Diagnosis of Cushing's Syndrome [J].
Loriaux, D. Lynn .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (15) :1451-1459
[8]   2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents [J].
Lurbe, Empar ;
Agabiti-Rosei, Enrico ;
Cruickshank, J. Kennedy ;
Dominiczak, Anna ;
Erdine, Serap ;
Hirth, Asle ;
Invitti, Cecilia ;
Litwin, Mieczyslaw ;
Mancia, Giuseppe ;
Pall, Denes ;
Rascher, Wolfgang ;
Redon, Josep ;
Schaefer, Franz ;
Seeman, Tomas ;
Sinha, Manish ;
Stabouli, Stella ;
Webb, Nicholas J. ;
Wuehl, Elke ;
Zanchetti, Alberto .
JOURNAL OF HYPERTENSION, 2016, 34 (10) :1887-1920
[9]   Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis [J].
Monticone, Silvia ;
D'Ascenzo, Fabrizio ;
Moretti, Claudio ;
Williams, Tracy Ann ;
Veglio, Franco ;
Gaita, Fiorenzo ;
Mulatero, Paolo .
LANCET DIABETES & ENDOCRINOLOGY, 2018, 6 (01) :41-50
[10]   Guidelines for primary aldosteronism: uptake by primary care physicians in Europe [J].
Mulatero, Paolo ;
Monticone, Silvia ;
Burrello, Jacopo ;
Veglio, Franco ;
Williams, Tracy A. ;
Funder, John .
JOURNAL OF HYPERTENSION, 2016, 34 (11) :2253-2257