Skin diseases associated with atopic dermatitis

被引:45
作者
Fenner, Justine [1 ]
Silverberg, Nanette B. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Mt Sinai West, Dept Dermatol, New York, NY 10029 USA
关键词
OF-FUNCTION MUTATIONS; STAPHYLOCOCCUS-AUREUS COLONIZATION; EXTENSIVE PITYRIASIS ALBA; ICHTHYOSIS VULGARIS; ALOPECIA-AREATA; MOLLUSCUM CONTAGIOSUM; FILAGGRIN MUTATIONS; INCREASED RISK; CONTACT SENSITIZATION; METHICILLIN-RESISTANT;
D O I
10.1016/j.clindermatol.2018.05.004
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disorder, characterized by an abnormal skin barrier, immune dysfunction, and an altered skin microbiome. AD may be seen in conjunction with a variety of other skin disorders due to the complex pathogenesis of AD, involving genetic and environmental factors that are associated with immune dysfunction, barrier defects, and altered skin micro-biomes. Skin disorders associated with AD include diseases sharing similar genetic origins like ichthyosis vulgaris, infectious diseases such as impetigo, and eczema herpeticum, in addition to the cutaneous autoimmune diseases, alopecia areata, and vitiligo. AD is also often linked to such benign conditions as pityriasis alba and keratosis pilaris. This review discusses the cutaneous comorbidities of AD and their relationship via their occurrence in conjunction with atopic dermatitis. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码:631 / 640
页数:10
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