Fever of unknown origin: Clinical overview of classic and current concepts

被引：53
作者：
Cunha, Burke A. [1 ,2 ]
机构：
[1] Winthrop Univ Hosp, Div Infect Dis, Mineola, NY 11501 USA
[2] SUNY Stony Brook, Sch Med, Stony Brook, NY 11794 USA
来源：
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2007年 / 21卷 / 04期
关键词：
D O I：
10.1016/j.idc.2007.09.002
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Fever of unknown origin (FUO) refers to disorders that present with prolonged and perplexing fevers that are difficult to diagnose. This article presents a clinical overview of classic and current causes of FUOs, which may be due to infectious, rheumatic/inflammatory, neoplastic, or miscellaneous disorders. Comprehensive but nonfocused diagnostic testing is ineffective and should be avoided. The FUO workup should be directed by the key history physical, and laboratory findings in clinical presentation. The clinical syndromic approach in the differential diagnosis of FUOs is emphasized, and the diagnostic importance and significance of fever patterns are discussed.
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收藏
页码：867 / +
页数：50
相关论文
共 164 条
[11]  
BAILEY EM, 1989, LANCET, V2, P986
[12]  
BAUGHMAN RP, 2006, SARCOIDOSIS
[13]   Familial Mediterranean fever [J].
Ben-Chetrit, E ;
Levy, M .
LANCET, 1998, 351 (9103) :659-664
[14]   SYSTEMIC MANIFESTATIONS OF HYPERNEPHROMA - REVIEW OF 273 CASES [J].
BERGER, L ;
SINKOFF, MW .
AMERICAN JOURNAL OF MEDICINE, 1957, 22 (05) :791-796
[15]   MEDIASTINAL AND SUPRACLAVICULAR LYMPHADENITIS AND PNEUMONITIS DUE TO CHLAMYDIA-TRACHOMATIS SEROVARS L1 AND L2 [J].
BERNSTEIN, DI ;
HUBBARD, T ;
WENMAN, WM ;
JOHNSON, BL ;
HOLMES, KK ;
LIEBHABER, H ;
SCHACHTER, J ;
BARNES, R ;
LOVETT, MA .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (24) :1543-1546
[16]   An uncommon cause of fever in the elderly: late-onset systemic lupus erythematosus [J].
Beyan, E ;
Uzuner, A ;
Beyan, C .
CLINICAL RHEUMATOLOGY, 2003, 22 (06) :481-483
[17]   A prospective multicenter study on fever of unknown origin - The yield of a structured diagnostic protocol [J].
Bleeker-Rovers, Chantal P. ;
Vos, Fidel J. ;
de Kleijn, Elisabeth M. H. A. ;
Mudde, Aart H. ;
Dofferhoff, Ton S. M. ;
Richter, Clemens ;
Smilde, Tineke J. ;
Krabbe, Paul F. M. ;
Oyen, Wim J. G. ;
van der Meer, Jos W. M. .
MEDICINE, 2007, 86 (01) :26-38
[18]   Clinical value of [18F]fluoro-deoxyglucose positron emission tomography for patients with fever of unknown origin [J].
Blockmans, D ;
Knockaert, D ;
Maes, A ;
De Caestecker, J ;
Stroobants, S ;
Bobbaers, H ;
Mortelmans, L .
CLINICAL INFECTIOUS DISEASES, 2001, 32 (02) :191-196
[19]   Chikungunya: an epidemic in real time [J].
Bodenmann, Patrick ;
Genton, Blaise .
LANCET, 2006, 368 (9531) :258-258
[20]  
Bouza E, 2007, FEVER UNKNOWN ORIGIN, P79
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