Seasonal variation of mogrosides in Lo Han Kuo (Siraitia grosvenori) fruits

被引：35
作者：
Li, Dianpeng
Ikeda, Tsuyoshi
Huang, Yonglin
Liu, Jinlei
Nohara, Toshihiro
Sakamoto, Tatsunori
Nonaka, Gen-Ichiro
机构：
[1] Kumamoto Univ, Fac Med & Pharmaceut Sci, Kumamoto 8620973, Japan
[2] Chinese Acad Sci, Guanxi Inst Bot, Guilin 541006, Peoples R China
[3] Sakamoto Limestone Ind Co Ltd, Kumamoto 8650013, Japan
[4] Nonaka Usaien Pharmaceut Co Ltd, Saga 8400055, Japan
来源：
JOURNAL OF NATURAL MEDICINES | 2007年 / 61卷 / 03期
关键词：
Siraitia grosvenori; Lo Han Kuo; mogrosides; HPLC; TLC; seasonal variation;
D O I：
10.1007/s11418-006-0130-7
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Mogrosides at different growth stages of Lo Han Kuo (Siraitia grosvenori) fruits were analyzed qualitatively and quantitatively using TLC and HPLC. The results show that we can clearly discriminate the seasonal variation of the main mogrosides in Lo Han Kuo fruits: mogroside V is the main constituent of ripe fruits, while mogrosides III and II E are the leading components in unripe fruits. A comprehensive validation (sensitivity, linearity, reproducibility and recovery) of an HPLC method that can simultaneously determine the content of mogrosides V, III and II E was conducted. This method is proposed as a simple, rapid and accurate method for quantitative determination of the mogroside V, mogroside III and mogroside II E content in various samples of Lo Han Kuo (S. grosvenori) fruits.
引用
收藏
页码：307 / 312
页数：6
相关论文
共 13 条
[1]  
[Anonymous], 1996, ACTA BOT SIN
[2]  
CHANG Q, 1994, CHIN J MAG RES, V11, P43
[3]   SWEET CUCURBITANE GLYCOSIDES FROM FRUITS OF SIRAITIA-SIAMENSIS (CHI-ZILUO-HAN-GUO), A CHINESE FOLK MEDICINE [J].
KASAI, R ;
NIE, RL ;
NASHI, K ;
OHTANI, K ;
ZHOU, J ;
TAO, GD ;
TANAKA, O .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1989, 53 (12) :3347-3349
[4]   POTENTIAL SWEETENING AGENTS OF PLANT-ORIGIN .6. HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF THE MAJOR SWEET PRINCIPLE OF LO HAN KUO FRUITS [J].
MAKAPUGAY, HC ;
NANAYAKKARA, NPD ;
SOEJARTO, DD ;
KINGHORN, AD .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1985, 33 (03) :348-350
[5]  
MATSUMOTO K, 1990, CHEM PHARM BULL, V38, P2030, DOI 10.1248/cpb.38.2030
[6]  
SI JY, 1994, YAOXUE XUEBAO, V29, P158
[7]   Triterpene glycosides of Siraitia grosvenori inhibit rat intestinal maltase and suppress the rise in blood glucose level after a single oral administration of maltose in rats [J].
Suzuki, YA ;
Murata, Y ;
Inui, H ;
Sugiura, M ;
Nakano, Y .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (08) :2941-2946
[8]   Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori [J].
Takasaki, M ;
Konoshima, T ;
Murata, Y ;
Sugiura, M ;
Nishino, H ;
Tokuda, H ;
Matsumoto, K ;
Kasai, R ;
Yamasaki, K .
CANCER LETTERS, 2003, 198 (01) :37-42
[9]   STUDIES ON THE CONSTITUENTS OF FRUCTUS MOMORDICAE .1. ON THE SWEET PRINCIPLE [J].
TAKEMOTO, T ;
ARIHARA, S ;
NAKAJIMA, T ;
OKUHIRA, M .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1983, 103 (11) :1151-1154
[10]  
Takeo Eiichiro, 2002, J Atheroscler Thromb, V9, P114
12