Conjugate reduction of α,β-unsaturated ketones with hydrosilane mediated by copper(I) salt

被引：52

作者：

Mori, A ^{[1
]}

Fujita, A ^{[1
]}

Kajiro, H ^{[1
]}

Nishihara, Y ^{[1
]}

Hiyama, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Resources Utilizat Res Lab, Yokohama, Kanagawa 2268503, Japan

来源：

TETRAHEDRON | 1999年 / 55卷 / 15期

关键词：

copper and compounds; ketones; reduction; silicon and compounds;

D O I：

10.1016/S0040-4020(99)00141-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reduction of several alpha,beta-unsaturated ketones with dimethylphenylsilane and 10-100 mol% of CuF(PPh3)(3). 2EtOH or CuCl/PPh3/Bu4NF proceeds in a 1,4-selective manner to give the corresponding saturated ketones in up to >99% yield. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4573 / 4582

页数：10

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