Nanomaterials toxin contamination in laboratories and potential harmful effects of their products: a review

被引:6
作者
Akbarzadeh, Abolfazl [1 ,2 ,3 ]
Mohammadhosseini, Majid [4 ]
Abadi, Azam Jafari Najaf [1 ]
Hasanzadeh, Arash [2 ]
Abasi, Elham [2 ]
Aberoumandi, Seyed Mohsen [5 ]
Panahi, Yunes [5 ]
机构
[1] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz 5154853431, Iran
[2] Tabriz Univ Med Sci, Stem Cell Res Ctr, Tehran, Iran
[3] USERN, Tabriz, Iran
[4] Islamic Azad Univ, Shahrood Branch, Dept Chem, Shahrood, Iran
[5] Baqiyatallah Univ Med Sci, Chem Injuries Res Ctr, Tabriz, Iran
关键词
Nanotoxicology; nanoparticles; toxic effect; oxidative stress; DNA damage; IRON-OXIDE NANOPARTICLES; SILVER NANOPARTICLES; GOLD NANOPARTICLES; TITANIUM-DIOXIDE; GENE-EXPRESSION; DNA-DAMAGE; TOXICITY; EXPOSURE; MICE; CELLS;
D O I
10.1080/15569543.2016.1223693
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Latest nanotechnological advances propose that nanoparticles have been predictable to be used in different fields. Nanomaterials are used in a extensive diversity of commercial goods for example electronic components, sports equipment, sun creams and biomedical applications. Employing nanoparticles in medicine is ever increasing, and it is significant to know their targeted and non-targeted effects. A number of nanoparticles seem to be talented to translocate from their site of deposition to far sites, for instance the blood and the brain, and these materials can cause DNA damage to cells cultured underneath a cellular barrier without crossing this barrier. So the study of these nanosized material toxicities in the blood, brain, skin, liver, etc. seems to be necessary.
引用
收藏
页码:180 / 186
页数:7
相关论文
共 58 条
  • [1] Silver nanoparticles: Synthesis methods, bio-applications and properties
    Abbasi, Elham
    Milani, Morteza
    Aval, Sedigheh Fekri
    Kouhi, Mohammad
    Akbarzadeh, Abolfazl
    Nasrabadi, Hamid Tayefi
    Nikasa, Parisa
    Joo, San Woo
    Hanifehpour, Younes
    Nejati-Koshki, Kazem
    Samiei, Mohammad
    [J]. CRITICAL REVIEWS IN MICROBIOLOGY, 2016, 42 (02) : 173 - 180
  • [2] Dendrimers: synthesis, applications, and properties
    Abbasi, Elham
    Aval, Sedigheh Fekri
    Akbarzadeh, Abolfazl
    Milani, Morteza
    Nasrabadi, Hamid Tayefi
    Joo, Sang Woo
    Hanifehpour, Younes
    Nejati-Koshki, Kazem
    Pashaei-Asl, Roghiyeh
    [J]. NANOSCALE RESEARCH LETTERS, 2014, 9 : 1 - 10
  • [3] Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata
    Aruoja, Villem
    Dubourguier, Henri-Charles
    Kasemets, Kaja
    Kahru, Anne
    [J]. SCIENCE OF THE TOTAL ENVIRONMENT, 2009, 407 (04) : 1461 - 1468
  • [4] ASMATULU R, 2009, SAMPE FALL TECHN C W, P1
  • [5] Comparison between Effects of Free Curcumin and Curcumin Loaded NIPAAm-MAA Nanoparticles on Telomerase and PinX1 Gene Expression in Lung Cancer Cells
    Badrzadeh, Fariba
    Akbarzadeh, Abolfazl
    Zarghami, Nosratollah
    Yamchi, Mohammad Rahmati
    Zeighamian, Vahide
    Tabatabae, Fateme Sadate
    Taheri, Morteza
    Kafil, Hossein Samadi
    [J]. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 2014, 15 (20) : 8931 - 8936
  • [6] Assessing susceptibility from early-life exposure to carcinogens
    Barton, HA
    Cogliano, VJ
    Flowers, L
    Valcovic, L
    Setzer, RW
    Woodruff, TJ
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2005, 113 (09) : 1125 - 1133
  • [7] Inorganic Nanoparticles in Cancer Therapy
    Bhattacharyya, Sanjib
    Kudgus, Rachel A.
    Bhattacharya, Resham
    Mukherjee, Priyabrata
    [J]. PHARMACEUTICAL RESEARCH, 2011, 28 (02) : 237 - 259
  • [8] BIRRINGER R, 1994, P NATO ASI E, P157
  • [9] Nanomaterials and nanoparticles: Sources and toxicity
    Buzea, Cristina
    Pacheco, Ivan I.
    Robbie, Kevin
    [J]. BIOINTERPHASES, 2007, 2 (04) : MR17 - MR71
  • [10] The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles
    Chang, Ya-Nan
    Zhang, Mingyi
    Xia, Lin
    Zhang, Jun
    Xing, Gengmei
    [J]. MATERIALS, 2012, 5 (12): : 2850 - 2871