A Histopathological Study of Bulbar Conjunctival Flaps Occurring in 2 Contact Lens Wearers

被引:3
作者
Markoulli, Maria [1 ,2 ]
Francis, Ian C. [2 ,3 ]
Yong, Jim [4 ]
Jalbert, Isabelle [2 ]
Carnt, Nicole [1 ]
Cole, Nerida [1 ,2 ]
Papas, Eric [1 ,2 ,5 ]
机构
[1] Univ New S Wales, Brien Holden Vis Inst, Sydney, NSW 2052, Australia
[2] Univ New S Wales, Sch Optometry & Vis Sci, Sydney, NSW 2052, Australia
[3] Prince Wales Hosp, Dept Ophthalmol, Sydney, NSW, Australia
[4] S Western Sydney Area Pathol Serv, Sydney, NSW, Australia
[5] Vis Cooperat Res Ctr, Sydney, NSW, Australia
关键词
bulbar conjunctiva; flaps; contact lens; biopsy; histopathology; IMPRESSION CYTOLOGY; OCULAR SURFACE;
D O I
10.1097/ICO.0b013e318207ec82
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To study the histopathology of paralimbal bulbar conjunctival flaps occurring secondary to soft contact lens wear. Methods: Slit-lamp biomicroscopy using sodium fluorescein, cobalt blue light, and a Wratten filter was used to observe the presence, location, and dimensions of bulbar conjunctival flaps presenting in a cohort of contact lens wearers. Two subjects who exhibited such flaps agreed to undergo conjunctival biopsy. Tissue samples, obtained from the region of the flap, and an adjacent unaffected area were processed by standard histopathological methods. Results: In the first subject, analysis of the flap tissue showed even collagen distribution and overall normal histology. The flap of the second subject displayed a mild focal increase in collagen and mild degeneration of collagen, but no increase in elastic tissue. Conjunctival epithelium was normal in both cases. Conclusions: In these 2 subjects, conjunctival flap tissue either was normal or showed only minimal abnormality. There is insufficient evidence for significant pathological change on the time scale of this study.
引用
收藏
页码:1037 / 1041
页数:5
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