Facile synthesis of spiroisoquinolines based on photocycloaddition of isoquinoline-1,3,4-trione with oxazoles

被引：21
作者：
Huang, Chengmei [1 ]
Yu, Haitao [1 ]
Miao, Zhengrui [1 ]
Zhou, Jie [1 ]
Wang, Shuai [1 ]
Fun, Hoong-Kun [2 ]
Xu, Jianhua [1 ]
Zhang, Yan [1 ]
机构：
[1] Nanjing Univ, Minist Educ China, Key Lab Analyt Chem Life Sci, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China
[2] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm Penang 11800, Malaysia
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 10期
基金：
中国国家自然科学基金;
关键词：
ALDOSE REDUCTASE INHIBITORS; PHOTOINDUCED REACTIONS; 2+2 CYCLOADDITIONS; O-QUINONES; DERIVATIVES; 1-ACETYLISATIN; ROUTE; REGIO; DIASTEREOSELECTIVITY; REGIOSELECTIVITY;
D O I：
10.1039/c1ob05143a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Photocycloaddition of isoquinoline-1,3,4-trione and 5-methoxyoxazoles affords spiroisoquinolineoxetanes with high regio- and diastereoselectivity. The spiroisoquinolineoxetanes can be conveniently converted into novel spiroisoquinolineoxazoline derivatives through acid catalyzed sequential reactions.
引用
收藏
页码：3629 / 3631
页数：3
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