Unsupervised Event Graph Representation and Similarity Learning on Biomedical Literature

被引:11
作者
Frisoni, Giacomo [1 ]
Moro, Gianluca [1 ]
Carlassare, Giulio
Carbonaro, Antonella [1 ]
机构
[1] Univ Bologna, Dept Comp Sci & Engn DISI, I-40126 Bologna, Italy
关键词
event embedding; graph representation learning; graph similarity learning; metric learning; graph kernels; graph neural networks; event extraction; biomedical text mining; EXTRACTION; DISTANCE; SYSTEM;
D O I
10.3390/s22010003
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The automatic extraction of biomedical events from the scientific literature has drawn keen interest in the last several years, recognizing complex and semantically rich graphical interactions otherwise buried in texts. However, very few works revolve around learning embeddings or similarity metrics for event graphs. This gap leaves biological relations unlinked and prevents the application of machine learning techniques to promote discoveries. Taking advantage of recent deep graph kernel solutions and pre-trained language models, we propose Deep Divergence Event Graph Kernels (DDEGK), an unsupervised inductive method to map events into low-dimensional vectors, preserving their structural and semantic similarities. Unlike most other systems, DDEGK operates at a graph level and does not require task-specific labels, feature engineering, or known correspondences between nodes. To this end, our solution compares events against a small set of anchor ones, trains cross-graph attention networks for drawing pairwise alignments (bolstering interpretability), and employs transformer-based models to encode continuous attributes. Extensive experiments have been done on nine biomedical datasets. We show that our learned event representations can be effectively employed in tasks such as graph classification, clustering, and visualization, also facilitating downstream semantic textual similarity. Empirical results demonstrate that DDEGK significantly outperforms other state-of-the-art methods.
引用
收藏
页数:34
相关论文
共 50 条
[41]   Application of deep metric learning to molecular graph similarity [J].
Coupry, Damien E. ;
Pogany, Peter .
JOURNAL OF CHEMINFORMATICS, 2022, 14 (01)
[42]   Application of deep metric learning to molecular graph similarity [J].
Damien E. Coupry ;
Peter Pogány .
Journal of Cheminformatics, 14
[43]   Graph Reconfigurable Pooling for Graph Representation Learning [J].
Li, Xiaolin ;
Xu, Qikui ;
Xu, Zhenyu ;
Zhang, Hongyan ;
Xu, Li .
IEEE TRANSACTIONS ON EMERGING TOPICS IN COMPUTING, 2024, 12 (01) :139-149
[44]   A multi-graph representation for event extraction [J].
Huang, Hui ;
Chen, Yanping ;
Lin, Chuan ;
Huang, Ruizhang ;
Zheng, Qinghua ;
Qin, Yongbin .
ARTIFICIAL INTELLIGENCE, 2024, 332
[45]   Inexact Graph Representation Learning [J].
Duan, Yijun ;
Liu, Xin ;
Jatowt, Adam ;
Yu, Hai-tao ;
Lynden, Steven ;
Matono, Akiyoshi .
2024 INTERNATIONAL JOINT CONFERENCE ON NEURAL NETWORKS, IJCNN 2024, 2024,
[46]   Effective type label-based synergistic representation learning for biomedical event trigger detection [J].
Hao, Anran ;
Yuan, Haohan ;
Hui, Siu Cheung ;
Su, Jian .
BMC BIOINFORMATICS, 2024, 25 (01)
[47]   Graph Representation Learning Hamilton [J].
Hamilton W.L. .
Synthesis Lectures on Artificial Intelligence and Machine Learning, 2020, 14 (03) :1-159
[48]   Graph-based Representation of Audio signals for Sound Event Classification [J].
Aironi, Carlo ;
Cornell, Samuele ;
Principi, Emanuele ;
Squartini, Stefano .
29TH EUROPEAN SIGNAL PROCESSING CONFERENCE (EUSIPCO 2021), 2021, :566-570
[49]   An End-to-End Multiplex Graph Neural Network for Graph Representation Learning [J].
Liang, Yanyan ;
Zhang, Yanfeng ;
Gao, Dechao ;
Xu, Qian .
IEEE ACCESS, 2021, 9 :58861-58869
[50]   Ricci Curvature-Based Graph Sparsification for Continual Graph Representation Learning [J].
Zhang, Xikun ;
Song, Dongjin ;
Tao, Dacheng .
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 35 (12) :17398-17410