Interactions between the neuropeptide Y system and the hypothalamic-pituitary-adrenal axis

被引：74
|
作者：
Krysiak, R [1 ]
Obuchowicz, E [1 ]
Herman, ZS [1 ]
机构：
[1] Silesian Univ, Sch Med, Dept Clin Pharmacol, PL-40752 Katowice, Poland
来源：
EUROPEAN JOURNAL OF ENDOCRINOLOGY | 1999年 / 140卷 / 02期
关键词：
D O I：
10.1530/eje.0.1400130
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The aim of this paper is to review the present knowledge of interactions between the neuropeptide Y (NPY) system and the hypothalamic-pituitary-adrenal (HPA) axis. On the basis of in vitro and in vivo studies of various animal species, we review the effects of NPY on all levels of HPA axis activity. We also describe the effects of glucocorticosteroids on the NPY system in the hypothalamus, including interactions between glucocorticosteroids and insulin. On the basis of available literature, we discuss the role of these interactions in the control of food intake and in the pathogenesis of obesity.
引用
收藏
页码：130 / 136
页数：7
相关论文
共 50 条
  • [1] Interactions between the neuropeptide Y system and the hypothalamic-pituitary-adrenal axis (vol 140, pg 130, 1999)
    Krysiak, R
    Obuchowicz, E
    Herman, ZS
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1999, 140 (03) : 269 - 269
  • [2] EFFECT OF NEUROPEPTIDE-Y ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN THE DOG
    INOUE, T
    INUI, A
    OKITA, M
    SAKATANI, N
    OYA, M
    MORIOKA, H
    MIZUNO, N
    OIMOMI, M
    BABA, S
    LIFE SCIENCES, 1989, 44 (15) : 1043 - 1051
  • [3] STRUCTURAL REQUIREMENTS FOR THE EFFECTS OF NEUROPEPTIDE-Y ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN THE DOG
    MIURA, M
    INUI, A
    TERANISHI, A
    HIROSUE, Y
    NAKAJIMA, M
    OKITA, M
    INOUE, T
    BABA, S
    KASUGA, M
    NEUROPEPTIDES, 1992, 23 (01) : 15 - 18
  • [4] Interactions between the stimulated hypothalamic-pituitary-adrenal axis and leptin in humans
    Nye, EJ
    Bornstein, SR
    Grice, JE
    Tauchnitz, R
    Hockings, GI
    Strakosch, CR
    Jackson, RV
    Torpy, DJ
    JOURNAL OF NEUROENDOCRINOLOGY, 2000, 12 (02) : 141 - 145
  • [5] INTERACTIONS BETWEEN CYTOKINES AND THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS DURING STRESS
    ARIMURA, A
    TAKAKI, A
    KOMAKI, G
    MODELS OF NEUROPEPTIDE ACTION, 1994, 739 : 270 - 281
  • [6] HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    HONOUR, JW
    RESPIRATORY MEDICINE, 1994, 88 : 9 - 15
  • [7] THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    FEEK, CM
    MARANTE, DJ
    EDWARDS, CRW
    CLINICS IN ENDOCRINOLOGY AND METABOLISM, 1983, 12 (03): : 597 - 618
  • [8] The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats
    Jaszberenyi, Miklos
    Bagosi, Zsolt
    Csabafi, Krisztina
    Palotai, Miklos
    Telegdy, Gyula
    REGULATORY PEPTIDES, 2014, 188 : 46 - 51
  • [9] INTERACTIONS BETWEEN LIPOCORTIN-1 AND THE HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS
    SUDLOW, AW
    CAREY, F
    ROTHWELL, NJ
    BRITISH JOURNAL OF PHARMACOLOGY, 1993, 110 : P73 - P73
  • [10] HYPOTHALAMIC-PITUITARY-ADRENAL AXIS AND IMMUNE-SYSTEM
    SAVASTANO, S
    TOMMASELLI, AP
    VALENTINO, R
    MARINIELLO, P
    COLAO, A
    MEROLA, B
    COVELLI, V
    LOMBARDI, G
    EOS-RIVISTA DI IMMUNOLOGIA ED IMMUNOFARMACOLOGIA, 1993, 13 (01): : 111 - 112
12345