Doxorubicin-loaded Fe3O4@SiO2 Nanoparticles as Magnetic Targeting Agents for Combined Photothermal-chemotherapy of Cancer

被引：11
作者：
Ding, Bei [1 ]
Shen, Song [1 ]
Wu, Lin [2 ]
Qi, Xueyong [1 ]
Ni, Haihua [3 ]
Gei, Yanru [1 ]
机构：
[1] Jiangsu Univ, Sch Pharm, Zhenjiang 212013, Peoples R China
[2] Jiangsu Univ, Affiliated Hosp, Zhenjiang 212013, Peoples R China
[3] Haiji Pharmaceut Co, Yangtze River Pharmaceut Grp, Taizhou 225300, Peoples R China
来源：
CHEMISTRY LETTERS | 2015年 / 44卷 / 06期
基金：
中国国家自然科学基金;
关键词：
GRAPHENE OXIDE; THERAPY; ABLATION; CELLS;
D O I：
10.1246/cl.150104
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Specific photothermal-chemotherapy is a promising tool in the treatment of the cancer. We developed silica-coated Fe3O4 nanoparticles as photothermal agents and magnetic targeting drug delivery system. Doxorubicin-loaded silica-coated Fe3O4 nanoparticles showed pH-responsive release properties. A synthetic antitumor effect of phototherrnal-chemotherapy was realized on MCF-7 cells.
引用
收藏
页码：858 / 860
页数：3
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