Diagnostic accuracy of the Finnish Diabetes Risk Chock for Score (FINDRISC) for undiagnosed T2DM in Peruvian population

被引:54
作者
Bernabe-Ortiz, Antonio [1 ,2 ]
Perel, Pablo [2 ]
Jaime Miranda, Juan [1 ,3 ]
Smeeth, Liam [2 ]
机构
[1] Univ Peruana Cayetano Heredia, CRON Ctr Excellence Chron Dis, Ave Armendariz 497, Lima 18, Peru
[2] London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, London WC1E 7HT, England
[3] Univ Peruana Cayetano Heredia, Dept Med, Sch Med, Lima 31, Peru
基金
英国惠康基金;
关键词
Diabetes mellitus; type; 2; Glucose tolerance test; Risk assessment; Screening; Diagnostic test; TYPE-2; VALIDATION; MELLITUS; DERIVATION; TOOLS; MODEL;
D O I
10.1016/j.pcd.2018.07.015
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. Materials and methods: A population-based study was conducted. T2DM and undiagnosed T2DM were defined using oral glucose tolerance test (OGTT). Risk scores assessed were FINDRISC, LA-FINDRISC and Peruvian Risk Score. Diagnostic accuracy of risk scores was estimated using the c-statistic and the area under the ROC curve (aROC). A simplified version of FINDRISC was also derived. Results: Data from 1609 individuals, mean age 48.2 (SD: 10.6), 810 (50.3%) women, were collected. A total of 176 (11.0%; 95%CI: 9.4%-12.5%) were classified as having T2DM, and 71 (4.7%; 95%CI: 3.7%-5.8%) were classified as having undiagnosed T2DM. Diagnostic accuracy of the FINDRISC (aROC =0.69), LA-FINDRISC (aROC = 0.68), and Peruvian Risk Score (aROC = 0.64) was similar (p=0.15). The simplified FINDRISC, with 4 variables, had a slightly better performance (aROC =0.71) than the other scores. Conclusion: The performance of FINDRISC, LA-FINDRISC and Peruvian Risk Score for undiagnosed T2DM was similar. A simplified FINDRISC can perform as well or better for undiagnosed T2DM. The FINDRISC may be useful to detect cases of undiagnosed T2DM in resource-constrained settings. (C) 2018 The Author(s). Published by Elsevier Ltd on behalf of Primary Care Diabetes Europe.
引用
收藏
页码:517 / 525
页数:9
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