Regional spectroscopy of paraffin-embedded breast cancer tissue using pulsed terahertz transmission imaging

被引:1
|
作者
Bowman, Tyler [1 ]
El-Shenawee, Magda [1 ]
Campbell, Lucas [2 ]
机构
[1] Univ Arkansas, Dept Elect Engn, Bell Engn Ctr 3217, Fayetteville, AR 72701 USA
[2] Northwest Arkansas Pathol Associates PA, 390 E Longview St, Fayetteville, AR 72703 USA
来源
OPTICAL INTERACTIONS WITH TISSUE AND CELLS XXVII | 2016年 / 9706卷
关键词
terahertz; time domain spectroscopy; breast cancer; terahertz spectroscopy;
D O I
10.1117/12.2212704
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This work seeks to obtain the properties of paraffin-embedded breast cancer tumor tissues using transmission imaging and spectroscopy. Formalin-fixed and paraffin-embedded breast tumors are first sectioned into slices of 20 mu m and 30 mu m and placed between two tsurupica slides. The slides are then scanned in a pulsed terahertz system using transmission imaging. The tissue regions in adjacent pathology section are compared to the transmission imaging scan in order to define a region of points over which to average the electrical properties results from the scan.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Pulsed Terahertz Imaging of Fresh and Fixed Human Breast Cancer Tissue
    Bowman, Tyler
    Bailey, Keith
    El-Shenawee, Magda
    2017 42ND INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER, AND TERAHERTZ WAVES (IRMMW-THZ), 2017,
  • [22] Technical approach for the study of the genetic evolution of breast cancer from paraffin-embedded tissue sections
    Chen, TP
    Dhingra, K
    Sahin, A
    Sneige, N
    Hortobagyi, G
    Aldaz, CM
    BREAST CANCER RESEARCH AND TREATMENT, 1996, 39 (02) : 177 - 185
  • [23] DEMONSTRATION OF GENE-AMPLIFICATION BY PCR IN ARCHIVAL PARAFFIN-EMBEDDED BREAST-CANCER TISSUE
    LONN, U
    LONN, S
    NILSSON, B
    SILFVERSWARD, C
    STENKVIST, B
    BREAST CANCER RESEARCH AND TREATMENT, 1994, 30 (02) : 147 - 152
  • [24] MiRNA expression profiling and validation in formalin-fixed paraffin-embedded breast cancer tissue
    Zhao, Yingchun
    Xiao, Jing
    Zhang, Hengwei
    Cao, Rui
    Deng, Caishu
    Gatalica, Zoran
    Silva, Ed
    Recker, Robert
    Xiao, Gary
    CANCER RESEARCH, 2009, 69
  • [25] Comparison of multivariate analysis methods for extracting the paraffin component from the paraffin-embedded cancer tissue spectra for Raman imaging
    Meksiarun, Phiranuphon
    Ishigaki, Mika
    Huck-Pezzei, Verena A. C.
    Huck, Christian W.
    Wongravee, Kanet
    Sato, Hidetoshi
    Ozaki, Yukihiro
    SCIENTIFIC REPORTS, 2017, 7
  • [26] ARGYRIA - MICROANALYTIC MORPHOLOGICAL CORRELATION USING PARAFFIN-EMBEDDED TISSUE
    LANDAS, S
    BONSIB, SM
    ELLERBROEK, R
    FISCHER, J
    ULTRASTRUCTURAL PATHOLOGY, 1986, 10 (02) : 129 - 135
  • [27] Comparison of multivariate analysis methods for extracting the paraffin component from the paraffin-embedded cancer tissue spectra for Raman imaging
    Phiranuphon Meksiarun
    Mika Ishigaki
    Verena A.C. Huck-Pezzei
    Christian W. Huck
    Kanet Wongravee
    Hidetoshi Sato
    Yukihiro Ozaki
    Scientific Reports, 7
  • [28] Analysis of the breast cancer methylome using formalin-fixed paraffin-embedded tumour
    Wong, Ee Ming
    Joo, JiHoon E.
    McLean, Catriona A.
    Baglietto, Laura
    English, Dallas R.
    Severi, Gianluca
    Wu, Hui-Chen
    Terry, Mary Beth
    Hopper, John L.
    Milne, Roger L.
    Giles, Graham G.
    Southey, Melissa C.
    BREAST CANCER RESEARCH AND TREATMENT, 2016, 160 (01) : 173 - 180
  • [29] Analysis of the breast cancer methylome using formalin-fixed paraffin-embedded tumour
    Ee Ming Wong
    JiHoon E. Joo
    Catriona A. McLean
    Laura Baglietto
    Dallas R. English
    Gianluca Severi
    Hui-Chen Wu
    Mary Beth Terry
    John L. Hopper
    Roger L. Milne
    Graham G. Giles
    Melissa C. Southey
    Breast Cancer Research and Treatment, 2016, 160 : 173 - 180
  • [30] Feasibility of using tissue microarray cores of paraffin-embedded breast cancer tissue for measurement of gene expression: a proof-of-concept study
    Drury, Suzanne
    Salter, Janine
    Baehner, Frederick L.
    Shak, Steven
    Dowsett, Mitch
    JOURNAL OF CLINICAL PATHOLOGY, 2010, 63 (06) : 513 - 517